BACKGROUND Klebsiella pneumoniae strains expressing ESBLs are a predominant cause of hospital acquired infections. Here we describe the molecular epidemiology of these isolates in a tertiary hospital in Tanzania, as potential pathogens for neonatal infections. METHODS Between April 2009 and March 2010 all Klebsiella pneumoniae isolates with phenotypic expression Extended Spectrum Beta Lactama...

Sixty-eight cefotaxime-resistant Escherichia coli isolates were recovered from different water environments in Northern Thailand. Isolates were mostly resistant to ceftazidime and aztreonam (>90%). The most common extended-spectrum β-lactamase-encoding gene was blaCTX-M-group 1 (75%) followed by blaCTX-M-group 9 (13.2%). The co-existence of blaCTX-M and AmpC-type β-lactamase genes was detected ...

Sixty-eight cefotaxime-resistant Escherichia coli isolates were recovered from different water environments in Northern Thailand. Isolates were mostly resistant to ceftazidime and aztreonam (>90%). The most common extended-spectrum β-lactamase-encoding gene was blaCTX-M-group 1 (75%) followed by blaCTX-M-group 9 (13.2%). The co-existence of blaCTX-M and AmpC-type β-lactamase genes was detected ...

Recent reports raised concerns about the role that farm stock may play in the dissemination of extended-spectrum β-lactamase (ESBL)-producing bacteria. This study characterized the ESBLs in two Escherichia coli and three Klebsiella pneumoniae subsp. pneumoniae isolates from cases of clinical bovine mastitis in the United Kingdom. Bacterial culture and sensitivity testing of bovine mastitic milk...

Antimicrobial-resistant bacteria and resistance determinants are of great concern to human veterinary medicine worldwide. Extended-spectrum ?-lactamase (ESBL)-producing resistant broad-spectrum cephalosporins. ESBL-producing isolates, including those carrying blaCTX, blaPER, blaVEB, blaGES, have been reported from rivers in several countries.1 In a study performed 2018, using next-generation se...

OBJECTIVE To investigate the molecular characteristics of extended-spectrum cephalosporin (ESC)-resistant Enterobacteriaceae collected during a cross-sectional study examining the prevalence and risk factors for faecal carriage of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae in humans living in areas with high or low broiler density. METHODS ESC-resistant Enterobacteriace...

OBJECTIVES To characterize a novel ceftazidime-hydrolysing CTX-M mutant, designated CTX-M-54, produced by Klebsiella pneumoniae clinical isolate BDK0419 and to investigate its genetic environment. METHODS Antimicrobial susceptibilities were determined by disc diffusion and agar dilution methods, and the double-disc synergy test was carried out. Detection of genes encoding class A beta-lactama...

This is the first report regarding the detection of blaCTX-M genes encoding CTX-M-1, CTX-M-15, and CTX-M-2 cefotaximases in clinical isolates of enterobacteria collected in hospitals in Bogotá, Colombia. During a period of 4 months in 2005, 117 isolates of enterobacteria having extended spectrum beta-lactamase (ESBL) phenotype were collected from nine third-level hospitals in Bogotá, Colombia. ...

defined by susceptibility to all of ciprofloxacin, co-trimoxazole and gentamicin) isolates was low (2.9%, 5/175). PCR and sequencing showed that the only extended-spectrum b-lactamase (ESBL)-producing O25b-ST131 isolate had blaCTX-M-14. Our results showed that O25b-ST131 exhibited a wide range of susceptibility patterns. Similar to previous studies, our findings showed that O25b-ST131 isolates ...

We characterized extended-spectrum beta-lactamases (ESBLs) and plasmid-mediated quinolone resistance (PMQR) in 32 Escherichia coli extended spectrum cephalosporin (ESC)-resistant clinical isolates from UK companion animals from several clinics. In addition, to investigate the possible dissemination of ESBL clinical isolates within a veterinary hospital, two ESBL-producing E. coli isolates from ...