Neighborhood matters: Response to EZH2 methyltransferase inhibitors Comment on: Amatangelo MD, et al. Cell Cycle 2013; 12:2113–9; PMID:23759589; http://dx.doi.org/10.4161/cc.25163 Kshipra M Gharpure and Anil K Sood*; Department of Gynecologic Oncology; The University of Texas MD Anderson Cancer Center; Houston, TX USA; Center for RNA Interference and Non-Coding RNAs; The University of Texas MD ...

ED FROM Nelson R, Edwards S, Tse B. Prophylactic nasogastric decompression after abdominal surgery. Cochrane Database Syst Rev 2007;(3):CD004929. Correspondence to: Prof R Nelson, Northern General Hospital, Sheffield, UK; [email protected]; [email protected] Source of funding: no external funding. c Clinical impact ratings: General surgery 6/7; Perioperative 7/7 Routine nasogastric t...

The lattice location of iron in thin-film, single-crystalline hexagonal GaN was studied by means of the emission channeling technique. Following 60-keV room-temperature implantation of the precursor isotope Mn at a dose of 1.0×10 cm and annealing up to 900°C, the angular distribution of β particles emitted by the radioactive isotope Fe was measured by a position-sensitive electron detector. The...

The lattice location of rare earth Er in single-crystalline hexagonal ZnO was studied by means of the emission channeling technique. Following 60-keV room-temperature implantation of the precursor isotope Tm at doses of 1.3−2.8×10 cm and annealing up to 900°C, the angular distribution of conversion electrons emitted by the radioactive isotope Er was measured by a position-sensitive electron det...

Neighborhood matters: Response to EZH2 methyltransferase inhibitors Comment on: Amatangelo MD, et al. Cell Cycle 2013; 12:2113–9; PMID:23759589; http://dx.doi.org/10.4161/cc.25163 Kshipra M Gharpure and Anil K Sood*; Department of Gynecologic Oncology; The University of Texas MD Anderson Cancer Center; Houston, TX USA; Center for RNA Interference and Non-Coding RNAs; The University of Texas MD ...

Circulating lipoproteins may offer interesting properties as therapeutic carriers for cytokines and hormones, in terms of both stability and bio-distribution. The fusion of apolipoprotein A-I with interleukin-15 (IL-15) targets the latter to high-density lipoproteins (HDLs). The bioactivity of this chimera can be further enhanced by creating triple fusions with IL-15 receptor α domain involved ...

The mAb AA4 binds to novel derivatives of the ganglioside GD1b on rat basophilic leukemia (RBL2H3) cells . Some of the gangliosides are located close to the high affinity IgE receptor (FCcRI), and binding of mAb AA4 inhibits FCERI-mediated histamine release . In the present study, mAb AA4 was found to bind exclusively to mast cells in all rat tissues examined . In vitro, within 1 min of mAb AA4...

The analysis of DNA microarray data is a rapidly evolving area of bioinformatics, and various types of microarray are emerging as some of the most exciting technologies for use in biological and clinical research. In recent years, microarray technology has been utilized in various applications such as the profiling of mRNAs, assessment of DNA copy number, genotyping, and detection of methylated...