1 Genes and Development Research Group and Department of Biochemistry and Molecular Biology, University of Calgary, Calgary, Alberta, T2N 4N1 Canada 2 Present address: Max-Planck-Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, D-01307 Dresden, Germany 3 Address correspondence to: Paul E. Mains Department of Biochemistry and Molecular Biology University of Calgary Calga...

Methods: Animals were divided into six groups receiving different treatments consisting of vehicle, EE (1.5 mg/kg/day i.m.) and Abana (3 g/kg/day orally) either alone or in combination for 3 or 6 weeks. After completion of the treatment schedules, effect of ACh, NA and Iso on the blood pressure vasopressor effects of NA on the hindquarter preparation was studied. Dopamine-β-hydroxylase (DBH) ac...

BACKGROUND A few recent studies have suggested that regulated on activation, normal T cell expressed and secreted (RANTES) polymorphisms (-403 G/A, -28C/G) are associated with asthma. However, there still existed studies which did not confirm these correlations. OBJECTIVE The objective of this study was to evaluate the relationship of RANTES and asthma using a meta-analysis. METHODS Pubmed,...

ICE1, a MYC-type transcription factor, has an important role in the induction of CBF3/DREB1A for regulation of cold signaling and tolerance. Here we reveal that serine 403 of ICE1 is involved in regulating the transactivation and stability of the ICE1 protein. Substitution of serine 403 by alanine enhanced the transactivational activity of ICE1 in Arabidopsis protoplasts. Over-expression of ICE...

[This corrects the article on p. 403 in vol. 40.].

[This corrects the article on p. 403 in vol. 11, PMID: 28260852.].

Background: The adalimumab biosimilar switch plan, actioned 2018-19 was one of the most complex all biologic switches across several specialties. Non-medical are considered to ensure best value medicines prescribed for patients in line with NICE Technology Appraisals. Objectives: This 2 year follow up review explores Rheumatology (R) comparison two other major specialisms; Dermatology and Gastr...

cer progression. However, for these results to be adopted in the clinical filed, it is very important that a large-sample-size study be brought conducted in a validation setting. The findings of this research finding suggest that PlGF may constitute a novel approach to colorectal cancer treatment. Several agents against PlGF have already developed or are currently under development. Among these...

BACKGROUND This study explores the influence of two functional genetic polymorphisms in the regulated on activation in normal T-cell expressed and secreted(RANTES) promoter on the risk of hepatocellular carcinoma (HCC) occurrence in patients with alcoholic or Hepatitis C Virus (HCV)-related cirrhosis. METHODS RANTES C-28G and G-403A promoter dimorphisms and RANTES serum levels were assessed i...