Iodine-125 (125I) seed implantation has been widely used for the treatment of unresectable advanced tumors. However, the molecular mechanisms underlying the tumor-suppressive effects of 125I irradiation have not been fully elucidated. The present study demonstrated that 125I irradiation suppresses cell viability and inhibits cell invasiveness of gastric cancer KATO-III and MKN45 cells. Further ...

The use of radioactive seed localization (RSL) as an alternative to wire localizations (WL) for nonpalpable breast lesions is rapidly gaining acceptance because of its advantages for both the patient and the surgical staff. This paper examines the initial experience with over 1,200 patients seen at a comprehensive cancer center. Radiation safety procedures for radiology, surgery, and pathology ...

Purpose We investigated the role of computed tomography (CT)-guided Iodine-125 (125I) seed implantation in combination with chemotherapy for the treatment of stage III non-small cell lung carcinoma (NSCLC). Material and methods The data from 182 patients with stage III NSCLC who were treated with radioactive 125I seed implantation between June 2002 and June 2009, and who received sequential p...

background: one of the key techniques for the preparation of 125i seeds is adsorption of 125i onto silver bits coated by palladium (pd). carriers played an important role in the adsorption of 125i on palladium. ki is used as a carrier for fixing of 125i onto silver wire bits coated with palladium. materials and methods: three procedures ki, koh, nh4oh were investigated for adsorption of 125i ac...

objectives this study examined 125i concentrations in the edible parts of five types of plants from different locations on farms with a similar climate. near zahedan, iran. background radioiodine 125i is an environmental contaminant that humans may consume in edible plants. the characteristics of 125i in plants are poorly understood. materials and methods the experiments used a mini-column appr...

Background: One of the key techniques for the preparation of 125I seeds is adsorption of 125I onto silver bits coated by palladium (pd). Carriers played an important role in the adsorption of 125I on palladium. KI is used as a carrier for fixing of 125I onto silver wire bits coated with palladium. Materials and Methods: Three procedures KI, KOH, NH4OH were investigated for adsorption of ...

OBJECTIVE To explore the therapeutic value of 3-D printing template-assisted 125I-seed implantation in the treatment of malignant liver tumors. MATERIALS AND METHODS Fifteen liver cancer patients with 47 total lesions were treated with 3-D printing template-assisted radioactive seed implantation (group A), and 25 liver-tumor patients with 66 total lesions were treated with 125I-seed implantat...

BACKGROUND Image-guidance systems allow accurate interfractional repositioning of IMRT treatments, however, these may require up to 15 minutes. Therefore intrafraction motion might have an impact on treatment precision. 3D geometric data regarding intrafraction prostate motion are rare; we therefore assessed its magnitude with pre- and post-treatment fiducial-based imaging with cone-beam-CT (CB...