Sao Paulo Med J. 2007;125(4):226-30. O R IG IN A L A R T IC L E Rozany Mucha Dufl oth

O R IG IN A L A R T IC L E Alexandre Rodrigues Guerzoni Érika Cristina Pavarino-Bertelli Moacir Fernandes de Godoy

3,4-Methylenedioxymethamphetamine (MDMA) is a widely abused illicit drug that can cause severe and even fatal adverse effects. However, interest remains for its possible clinical applications in posttraumatic stress disorder and anxiety treatment. Preclinical studies to determine MDMA’s safety are needed. We evaluated MDMA’s pharmacokinetics and metabolism in male rats receiving 2.5, 5, and 10 ...

O R IG IN A L A R T IC L E INTRODUCTION Gastroesophageal refl ux disease (GERD) in infancy presents significantly greater incidence in the population with associated neurological disease. There is a consensus that multifactorial events are involved in its etiopathogenesis, which makes it diffi cult to evaluate the results from treatment and to obtain adequate uniformity regarding the most appro...

Sao Paulo Med J. 2007;125(6):333-7. O R IG IN A L A R T IC L E Mauro Karnikowski

O R IG IN A L A R T IC L E INTRODUCTION Adequate postoperative analgesia is considered to be a major key for reducing pul monary morbidity and improving the outcome. Thoracic epidural anesthesia (TEA) has been proposed as a reliable analgesic method following thoracic surgery. Most of these benefi ts, however, relate to the postoperative or to the so-called perioperative period. Some case repor...