background: cytochrome p450 2c19 (cyp2c19) is a polymorphically expressed enzyme that shows marked interindividual and interethnic variation. cyp2c19*2 and cyp2c19*3 are the most frequently identified defective alleles in orientals and caucasian poor metabolizers (pm). the aim of this study was to investigate the frequencies of cyp2c19*1, cyp2c19*2 and cyp2c19*3 alleles and cyp2c19 genotypes in...

Aim. To evaluate characteristics of esophageal involvement in scleroderma. Methods. The study was prospective and concerned 194 patients with a definite systemic sclerosis. Gastroesophageal endoscopy and esophageal manometry were performed in all the cases. Results. Symptoms were present in 118 cases (60.8%); they were signs of GERD or dysphagia, respectively, in 94 (48.4%) and 91 patients (46....

Penelitian ini bertujuan untuk melihat dan mengetahui pengaruh langsung tidak kepemimpinan kompetensi terhadap etos kerja kinerja pegawai. Populasi dalam penelitian adalah seluruh pegawai Dinas Lingkungan Hidup Kehutanan Provinsi Riau yang berjumlah 118 orang. Adapun cara menentukan jumlah sampel menggunakan metode slovin, sehingga menjadi 91 responden teknik cluster random sampling purposive. ...

Background: Cytochrome P450 2C19 (CYP2C19) is a polymorphically expressed enzyme that shows marked interindividual and interethnic variation. CYP2C19*2 and CYP2C19*3 are the most frequently identified defective alleles in Orientals and Caucasian poor metabolizers (PM). The aim of this study was to investigate the frequencies of CYP2C19*1, CYP2C19*2 and CYP2C19*3 alleles and CYP2C19 genotypes in...

this study sought to develop a decision support system (dss) for assisting range managers to detect range condition and make informed decisions about feridan county rangelands. all plant species frequencies were measured in 31 range sites with various grazing histories using step point method. four hundred points along four perpendiculars 30 meters transects were measured in each site and grazi...

Purpose: The aim of this study was to compare a new method for the production of platelet-rich plasma (PRP), the plasma-rich-in-growth-factors kit (PRGF kit; G.A.C. Medicale San Antonio, Vitoria, Spain), with an established method, the Platelet Concentrate Collection System (PCCS; 3i/Implant Innovations, Palm Beach Gardens, FL) with respect to resulting cellular and growth factor contents. Mate...

The pathophysiology of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is poorly understood. Inflammatory and autoimmune mechanisms may play a role. We developed a murine model of experimental autoimmune prostatitis (EAP) that mimics the human phenotype of CP/CPPS. Eight-week-old mice were immunized subcutaneously with prostate-specific peptides in an emulsion of complete Freund's ad...

Materials and Methods: This was an open, prospective, randomized trial in COPD patients whose FEV1 (forced expiratory volume in 1 second) levels were between 80% and 50% predicted. A total of 44 patients who met the inclusion and exlusion criteria and who gave written informed consent were included in the study. At the end of the two week wash-out period, the patients were randomized to receive...