نتایج جستجو برای: 100 amino acids and positive charge pure charge 9

تعداد نتایج: 17062340  

Journal: :Journal of cell science 2010
Samuel C Wolff Ai-Dong Qi T Kendall Harden Robert A Nicholas

The P2Y(1) receptor is localized to the basolateral membrane of polarized Madin-Darby canine kidney (MDCK) cells. In the present study, we identified a 25-residue region within the C-terminal tail (C-tail) of the P2Y(1) receptor that directs basolateral sorting. Deletion of this sorting signal caused redirection of the receptor to the apical membrane, indicating that the region from the N-termi...

2014
Kyoung-Min Kim Hye Min Kim Won-Jae Lee Chang-Woo Lee Tae-il Kim Jong-Kwon Lee Jayoung Jeong Seung-Min Paek Jae-Min Oh

An attempt was made to control the surface charge of colloidal silica nanoparticles with 20 nm and 100 nm diameters. Untreated silica nanoparticles were determined to be highly negatively charged and have stable hydrodynamic sizes in a wide pH range. To change the surface to a positively charged form, various coating agents, such as amine containing molecules, multivalent metal cation, or amino...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تبریز - دانشکده شیمی 1392

in the present work, a simple and sensitive method was developed for determination of morphine and heroin using gold nanoparticles as resonance rayleigh scattering (rrs) and colorimetric technique’s probe. synthesized gold nanoparticles by sodium citrate reduction method have a negative charge layer on their surfaces because of self-assembled citrate anions on their surface. binding of morphin...

2010
Alexander Popkov Martin Breza

Chiral Ni(II) complexes are used for the preparation of carbon-11 or fluorine-18 enantiomerically pure α-amino acids for positron emission tomography (PET). They enable the selective monoalkylation of a glycine synthon with high stereoselectivity and the preparation of enantiomerically pure α-amino acids with quarternary α-carbon. Molecular modelling of non-, mono- and di-substituted complexes ...

Journal: :The Analyst 2016
Lindsay J Morrison Jennifer S Brodbelt

Characterization of all gas-phase charge sites of natively sprayed proteins and peptides is demonstrated using 193 nm UVPD. The high sequence coverage offered by UVPD is exploited for the accurate determination of charge sites in protein systems up to 18 kDa, allowing charge site to be studied as a function of protein conformation and the presence of disulfide bonds. Charging protons are found ...

Journal: :American journal of physiology. Cell physiology 2002
Oscar R Colegio Christina M Van Itallie Heather J McCrea Christoph Rahner James Melvin Anderson

Epithelia separate tissue spaces by regulating the passage of ions, solutes, and water through both the transcellular and paracellular pathways. Paracellular permeability is defined by intercellular tight junctions, which vary widely among tissues with respect to solute flux, electrical resistance, and ionic charge selectivity. To test the hypothesis that members of the claudin family of tight ...

Traditional vanadium batteries use pure sulfuric acid as electrolyte, but H2SO4 does not absorb enough vanadium ions to make the electrolyte an efficient energy source. This study investigates the effect of hydroxylation process on electrochemical and operational properties of carbon felt electrode in VOSO4 solution with an optimized supporting electrolyte (a mixture of six parts HCl and 2.5 pa...

2014
George A. Khoury James Smadbeck Phanourios Tamamis Andrew C. Vandris Chris A. Kieslich Christodoulos A. Floudas

We describe the development and testing of ab initio derived, AMBER ff03 compatible charge parameters for a large library of 147 noncanonical amino acids including β- and N-methylated amino acids for use in applications such as protein structure prediction and de novo protein design. The charge parameter derivation was performed using the RESP fitting approach. Studies were performed assessing ...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1989
M F Browner K Nakano A G Bang R J Fletterick

The cDNA for human muscle glycogen synthase encodes a protein of 737 amino acids. The primary structure of glycogen synthase is not related either to bacterial glycogen synthase or to any glycogen phosphorylase. All nine of the serines that are phosphorylated in the rabbit muscle enzyme in vivo are conserved in the human muscle sequence. The amino- and carboxyl-terminal fragments, which contain...

A. Mostoufi F. Beygi H. Eucefifar M. Fereidoonnezhad

The expression of heat shock protein 27 (Hsp27) as a chaperone protein, is increased in response to various stress stimuli such as anticancer chemotherapy. This phenomenon can lead to survive of the cells and causes drug resistance. In this study, a series of methanesulfonamide derivatives as dual Hsp27 and tubulin inhibitors in the treatment of cancer were applied to quantitative structure–act...

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