Introduction: The effect of esophageal distension (ED) on gastric motility has been well documented, but a few investigations have been carried out on the effect of ED on gastric secretion. The aim of this study was to investigate the effect of ED on gastric acid and pepsin secretion and the mechanism(s) involved. Methods: Male adult Wistar rats (200-240 g) were anesthetized with urethane (1...

on resolution refutations on pigeonhole principle formulas PHP n . Observe that PHP n has size N = Θ(n3), so the lower bound is, in fact, exp ( Ω ( 3 √ N )) in terms of formula size, and not truly exponential (by which we mean exp(Ω(N)) with the coefficient in the exponent scaling linearly with N ). In order to prove this lower bound we used the Prosecutor–Defendant game, where Prosecutor asks ...

the effect of epinephrine on triacylglycerol secretion was investigated in isolated rat hepatocytes. the effect appeared at concentrations of more than 1 µm and reached a plateau at 10 µm. epinephrine concentration for half of the maximal bioeffect (ec50) was about 1 µm. epineplrrine at a concentration of 10 µm suppressed triacylglycerol secretion by 33% and increased its cellular content by ap...

BACKGROUND In 1906, extracts of mucosa from the porcine upper small intestine were used by Moore et al. as a treatment for diabetes, hoping that “the pancreas secretion might be stimulated by the substance of the nature of a hormone yielded by the duodenal mucosa membrane” (1). In 1932, La Barre named the unidentified substance thought to exert this effect “incretin” (2). Thirty years later, Mc...

It has been shown that those factors which affect gastric acid secretion through the ventromedial and lateral nuclei of hypothalamus, can significantly alter centrally-mediated secretion. There is much evidence that glucose is among these factors that through a central mechanism can decrease induced acid secretion. It appears that this effect is mediated through glucose-sensitive neurons within...