Initial experiments involving mouse development employed single IP injections of 45 mg/kg sodium arsenate on one of days 6-12 of gestation and produced a spectrum of developmental defects. Embryotoxicity was indicated by high prenatal mortality and decreased fetal weights. A chelating agent, 2,3-dimercaptopropanol (BAL), was then employed in an attempt to alleviate the adverse effects of prenat...

Abstract Previous studies have suggested that arsenic crosses the placenta and affects fetus development. The study under consideration aims to show comparative ameliorative effect of Moringa oleifera leaf flower extracts against sodium arsenate induced toxicity mice. Pregnant mice (N=44) were kept in lab divided into eleven group from (A K) orally administered doses 6 mg/kg, 12 mg/kg for arsen...

The developmental origin of arsenate-induced renal agenesis was investigated. Pregnant Wistar rats were each injected once ip with 45 mgkg sodium arsenate a t day 10 (sperm day = day 0). Pregnancy was terminated a t various times following injection and the embryos recovered and serially sectioned. Renal agenesis resulted when the mesonephric duct failed to give rise to a ureteric bud with subs...

Background: The toxic effect of sodium arsenate on nervous system has been shown; but the protective effects several compounds against are not clear. This study aimed to investigate nicotine and bucladesine, two positive modulators neuronal function, toxicity avoidance memory impairment. Methods: Male mice (N=154) were assigned 22 groups (12 experimental 10 control) seven animals each treated a...

Whole embryo culture techniques were used to test the effects of sodium arsenate on the rates of DNA, RNA, and protein accumulation. Rat embryos were isolated on the 10th gestational day (sperm day = Day 0) either 4 or 24 hr after maternal injection. The cultivation period was for 24 or 42 hr. DNA, RNA, and protein values were not significantly different for in utero treatment 4 hr prior to dis...

Heavy metals are elements that mainly have a 5-22 gr.cm-3 specific gravity. Some of these essential micronutrients for plant growth (Such as Zinc (Zn), Copper (Cu), Manganese (Mn), Nickel (Ni) and Cobalt (Co)). other heavy metals, high toxicity properties such Lead (Pb), Cadmium (Cd) Mercury (Hg). In order to investigate the potential watercress (Nasturtium officinale) in uptake from nutrient s...

Arsenate was produced when anoxic Mono Lake water samples were amended with arsenite and either selenate or nitrate. Arsenite oxidation did not occur in killed control samples or live samples with no added terminal electron acceptor. Potential rates of anaerobic arsenite oxidation with selenate were comparable to those with nitrate ( approximately 12 to 15 mumol.liter(-1) h(-1)). A pure culture...