Human metabolism of the monoterpene cyclic ether 1,8-cineole was investigated in vitro and in vivo. In vitro, the biotransformation of 1,8-cineole was investigated by human liver microsomes and by recombinant cytochrome P450 enzymes coexpressed with human CYP-reductase in Escherichia coli cells. Besides the already described metabolite 2alpha-hydroxy-1,8-cineole we found another metabolite prod...

the chemical composition of the essential oils of flower at the pre-flowering, full-flowering and post-flowering stage of a. annua was analyzed by gc and gc/ms and sixty-two components were identified. the main compounds in the pre-flowering oil were β-myrcene (37.71%), 1, 8-cineole (16.11%) and camphor (14.97%). the full-flowering oil contained predominantly caryophyllene (19.4%), germacrene d...

Changes in essential oils (EOs) content and composition of lemon verbena leave at different packaging methods (packaged with air, nitrogen, or under vacuum) and during storage period (0, 2, 4, 6 and 8 months) were determined. All the samples were hydrodistilled every 2 months during storage for EO content evaluation. EO composition was determined by gas chromatography and gas chromatography-mas...

BACKGROUND Chlorhexidine belongs to a group of medicines called antiseptic antibacterial agents. Chlorhexidine is commonly used for the care and clean off the skin, hands, and wounds. In recent years, medicinal and aromatic plants have been used for prevention of disease, maintaining health, and improving disease in traditional and modern medicine as a medicament. According to recent research, ...

1,8-Cineole is a terpenoid present in many essential oil of plants with several pharmacological and biological effects, including antinociceptive, smooth muscle relaxant and ion channel activation. Also, 1,8-cineole blocked action potentials, reducing excitability of peripheral neurons. The objective of this work was to investigate effects of 1,8-cineole on Na(+) currents (INa(+)) in dissociate...

Achillea millefolium belong to the asteraceae family and from genus achillea. In this study essential oils were extracted from all aerial parts via hydro distillation (HD) method by clevenger set . By using of gas chromatography/mass spectrometry ( GC-MS) technique the chemicals component essential oil were identified. About 41 components with were identified which encompassed 97.66 percent of ...

Background & Aim: Different species from mint family (Lamiaceae) are used as spices and fragrance in food or as medicine against viral or microbial diseases in many countries for generation. Lamiaceae family contains 46 genus and 410 species. One of the valuable and medicinal species of this family is Ziziphora clinopodioides Lam. This species contains the essential o...

The present study was designed to determine the effects of the essential oil of Laurusnobilis L. (Lauraceae) and its three main components on α-glucosidase and reactive oxygenspecies scavenging activity. The chemical composition of the essential oil from Laurus nobilisL. leaves was analyzed by GC/GC-MS and resulted in the identification of 29 compounds,representing 99.18% of the total oil. 1,8-...