نتایج جستجو برای: 059
تعداد نتایج: 784 فیلتر نتایج به سال:
Yoga in Modern Hinduism: Hariharananda Aranya and Samkhyayoga, by Knut A. Jacobsen. London: Routledge, 2018. 242 pp., £97.99 (hb). ISBN 978-1-13808-059-1.
The neutral results of the SAINT II study1 dashed the hopes for a second ischemic stroke drug in the near future. Although this is certainly disappointing for stroke neurologists, a careful analysis of the NXY-059 development program reveals several deficiencies, which if properly addressed, might revitalize and strengthen the field of neuroprotection for acute ischemic stroke. This critique po...
Additional outcomes and subgroup analyses of NXY-059 for acute ischemic stroke in the SAINT I trial.
BACKGROUND AND PURPOSE NXY-059 is a free radical-trapping neuroprotectant demonstrated to reduce disability from ischemic stroke. We conducted analyses on additional end points and sensitivity analyses to confirm our findings. METHODS We randomized 1722 patients with acute ischemic stroke to a 72-hour infusion of placebo or intravenous NXY-059 within 6 hours of stroke onset. The primary outco...
Growing numbers of therapeutic antibodies offer excellent treatment strategies for many diseases. Elucidation of the interaction between a potential therapeutic antibody and its target protein by structural analysis reveals the mechanism of action and offers useful information for developing rational antibody designs for improved affinity. Here, we developed a rapid, high-yield cell-free system...
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