BACKGROUND Pemphigus vulgaris (PV) is a severe autoimmune blistering disorder characterized by the presence of pathogenic autoantibodies directed against desmoglein-3 (Dsg3), involving specific DR4 and DR6 alleles in Caucasians and DQ5 allele in Asians. The development of sequence-based predictive algorithms to identify potential Dsg3 epitopes has encountered limited success due to the paucity ...

OBJECTIVE The aim of this study was to evaluate the association of human leukocyte antigen (HLA)-DQ and HLA-DQA1/DQB1 alleles with Vogt-Koyanagi-Harada (VKH), providing further evidences on the genetic background of this disease. METHODS A comprehensive literature search was conducted on the relationship of HLA-DQ and/or HLA-DQA1/DQB1 alleles with VKH through PubMed, Embase, Cochrane Library,...

Pemphigus Vulgaris (PV) has one of the strongest known HLA disease associations. The majority PV patients studied carry either DRB1*0402 or DQB1*0503. However, studies on associations in have largely focused populations with specific ethnic backgrounds, often Ashkenazi Jewish (AJ) and non-Jewish Caucasians there are limited African descent. We investigated status 11 American (AA) comparison to ...

J Vasc Res 2003;40:179–208 DOI: 10.1159/000070715 Annual Meeting of the German Society for Microcirculation and Vascular Biology Munich, Germany, October 10–12, 2002 Editors: Barbara Walzog, Munich Jürgen Schymeinsky, Munich Prof. Dr. Barbara Walzog Department of Physiology, Ludwig-Maximilians-Universität Schillerstrasse 44 D–80336 München (Germany) Tel. +49 89 5996 414, Fax +49 89 5996 396, E-...

Robert C. Elson,1,2 Allen I. Selverston,1,2,3 Ramon Huerta,2,4 Nikolai F. Rulkov,2 Mikhail I. Rabinovich,2 and Henry D. I. Abarbanel2,5 1Department of Biology, University of California, San Diego, La Jolla, California 92093-0357 2Institute for Nonlinear Science, University of California, San Diego, La Jolla, California 92093-0402 3Instituto de Neurobiologica, Old San Juan, 00901, Puerto Rico 4E...

The parasitic inductance of multilayer ceramic capacitors (MLCCs) is becoming more important in the decoupling of high speed digital systems. There exists conflicting data and statements on the parasitic inductance of the MLCC. This work shows the measurement techniques of the inductance parameters, focusing mainly on the fixturing needed to accurately measure the chips. The effects of various ...

OBJECTIVE A major goal in genetic studies of type 1A diabetes is prediction of anti-islet autoimmunity and subsequent diabetes in the general population, as >85% of patients do not have a first-degree relative with type 1A diabetes. Given prior association studies, we hypothesized that the strongest candidates for enhancing diabetes risk among DR3-DQB1*0201/DR4-DQB1*0302 individuals would be al...