Autoantibodies are found in various pathological conditions such as autoimmune diseases, infectious and malignant tumors. However, their clinical implications have not yet been fully elucidated. Herein, we employed our proteome-wide cDNA library (HuPEX) which covers approximately 90% of the human transcriptome for autoantibody evaluation. In first step, screening was conducted upon pooled serum...

The plasma theophylline concentrations produced by 4 different slow release formulations, Theograd, Theodur, Theolair-SR and Rona-slophylline were measured over a 24-hr period in 8 healthy subjects. All 4 preparations maintained plasma levels over 12 hr and had similar AUC values when the difference in theophylline content was taken into account. Paired saliva and plasma theophylline concentrat...

BACKGROUND Diet might influence progression of hypertrophic cardiomyopathy (HCM). OBJECTIVE To investigate whether diet composition could alter clinical, biochemical, or echocardiographic variables in cats with HCM. ANIMALS Twenty-nine cats with HCM (International Small Animal Cardiac Health Council stage 1b) examined at a university teaching hospital. METHODS Randomized, placebo-controll...