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Daniel S. Poon, Ehud Reich, Victoria M. Smith, Judith Kingston, M. Ashwin Reddy, John L. Hungerford, Mandeep S. Sagoo 1 Royal London Hospital, London, UK 2 Moorfields Eye Hospital, London, UK 3 St. Bartholomew’s Hospital, London, UK 4 Great Ormond Street Hospital, London, UK 5 UCL Institute of Ophthalmology, London, UK * Address for reprints: Mr Mandeep S. Sagoo, MB, PhD, FRCS (Ed), FRCOphth, M...

Case report Here we report for the first time two patients with MKD revealed by a severe neonatal colitis. Both patients had chronic bloody diarrhea and failure to thrive, one patient since the age of one month and the other twelve days. Total parenteral nutrition was required. A marked elevation of acute phase reactants was present, and no evidence of infection was found. In patient 1, ileocol...

The University of Kent at Canterbury PSSRU Cornwallis Building, University of Kent at Canterbury, Canterbury, Kent CT2 7NF Tel: 01227 823963 Fax: 01227 827038 Email: [email protected] Site Director: Professor Ann Netten The London School of Economics PSSRU London School of Economics, Houghton Street, London WC2 2AE Tel: 020 7955 6238 Fax: 020 7955 6131 Email: [email protected] Site Director: Profe...

Neurodegeneration has diverse molecular causes. α-synucleinopathies are implicated in at least three neurodegenerative diseases: Parkinson’s Disease, Dementia with Lewy bodies and Multiple System Atrophy. Age-related increases in α-synuclein and its oligomers have been observed in short-lived Nothobranchius furzeri. N. furzeri Gonarezhou, with a lifespan of 9–12 weeks, is a new model organism f...

Increasing numbers of perinatally HIV (PHIV+)-infected youth are surviving into adulthood with better access to treatment. However, few studies examine positive outcomes in the face of adversity (resilience) for PHIV+ youth. Social Action Theory (SAT) provided the theoretical framework for this study of PHIV + youth in South Africa (SA), allowing examination of contextual, social, and self-regu...

BACKGROUND AND PURPOSE The differentiation between classic and atypical meningiomas may have implications in preoperative planning but may not be possible on the basis of conventional MR imaging. Our hypothesis was that classic and atypical meningiomas have different patterns of intratumoral water diffusion that will allow for differentiation between them. MATERIALS AND METHODS Preoperative d...

1. UCL Respiratory, Royal Free Campus, University College London, London, UK, NW3 2PF Corresponding Author TEL: 020 783

Context: Although kinematic analyses are helpful in describing movement differences between genders, kinetic data might further explain the predisposing factors contributing to potential injury during athletic landing maneuvers. Objective: To determine whether there are differences in knee moments between male and female varsity college soccer players during a single-leg landing. Design: Preexp...