This lecture begins with a discussion on secret-key and public-key cryptography, and then discusses One-Way Functions (OWF), and their importance in cryptography. Essentially, an OWF is easy to compute, but difficult to invert. A One-Way Permutation (OWP) is an OWF that permutes elements from a set. A Trap-Door Permutation (TDP) is essentially an OWP with certain information, that if disclosed,...

The Krüppel-like factor 4 (KLF4) gene is related to various biological processes including stem cell reprogramming and tumorigenesis. In this study, we identified and characterized a non-coding transcript of KLF4, which was designated KLF4‑003, in human liver tissue samples. KLF4‑003 was identified in a number of cell lines by reverse transcription PCR and DNA sequencing. Its expression levels ...

1Department of Biochemistry, King George’s Medical University, Lucknow-226 003, India 2Department of Pediatric Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi221005, India 3Department of Orthopedic Surgery, King George’s Medical University, Lucknow-226 003, India 4Department of Transfusion Medicine, King George’s Medical University, Lucknow-226 003, India 5Department ...

The aging population is a looming iceberg that threatens to sink the healthcare system as it sails through the 21st century. For the first time in history life expectancy in developed and developing countries has reached a limit that strains the very system that made longevity possible. Diseases that people used to die from last century are now conditions they live with, and the medical establi...

Phytocannabinoids that do not produce psychotropic effects are considered of special interest as novel therapeutic agents in CNS diseases. A cannabigerol quinone, the compound VCE-003, has been shown to alleviate symptoms in a viral model of multiple sclerosis (MS). Hence, we studied T cells and macrophages as targets for VCE-003 and its efficacy in an autoimmune model of MS. Proliferation, cel...

NB-003 and NB-003 gel formulations are oil-in-water nanoemulsions designed for use in bacterial infections. In vitro susceptibility of Propionibacterium acnes to NB-003 formulations and comparator drugs was evaluated. Both NB-003 formulations were bactericidal against all P. acnes isolates, including those that were erythromycin, clindamycin, and/or tetracycline resistant. In the absence of seb...