Background Nonalcoholic fatty liver disease is very frequent in type 2 diabetes, with increased risk of further development of liver fibrosis. Animal studies have shown that GLP-1 receptor agonists may reduce liver lipogenesis. However, data in humans are scarce. Objective To study the effect of liraglutide 1.2 mg/d on liver fat content (LFC) in patients with uncontrolled type 2 diabetes and ...

Neurabin and spinophilin are homologous protein phosphatase 1 and actin binding proteins that regulate dendritic spine function. A yeast two-hybrid analysis using the coiled-coil domain of neurabin revealed an interaction with Lfc, a Rho GEF. Lfc was highly expressed in brain, where it interacted with either neurabin or spinophilin. In neurons, Lfc was largely found in the shaft of dendrites in...

Rho GTPases regulate reorganization of actin and microtubule cytoskeletal structures during both interphase and mitosis. The timing and subcellular compartment in which Rho GTPases are activated is controlled by the large family of Rho GTP exchange factors (RhoGEFs). Here, we show that the microtubule-associated RhoGEF Lfc is required for the formation of the mitotic spindle during prophase/pro...

Processing and storage (4 ± 1°C) quality of Low-fat buffalo mozzarella cheese (BMC) was evaluated with carboxymethyl cellulose (CMC) as fat replacer. Five treatments of BMC viz. Control full-fat cheese (6.0% milk fat; CFFC), Control low-fat cheese (<0.5% MF) without CMC (CLFC), Low-fat cheese with 0.2% CMC (LFC-1), 0.4% CMC (LFC-2) and 0.6% CMC (LFC-3) were comparatively evaluated. Melting time...

A new Multi-Stage Fuzzy (MSF) controller based on Multi-objective Harmony Search Algorithm (MOHSA) is proposed in this paper to solve the Load Frequency Control (LFC) problem of power systems in deregulated environment. LFC problem are caused by load perturbations, which continuously disturb the normal operation of power system. The objectives of LFC are to mini small size the transient deviati...

In this study, the elevated temperature flexural strengths of lightweight foamed concrete (LFC) containing fly ash (FA) and polypropylene fiber (PF) was investigated experimentally and statistically. The variables included were the temperature degrees (in a range of 20 to 600°C), LFC densities of 600, 800, 1000, 1200 and 1400 kg/m3 and additive content. Two mixes were made by replacing 15% and ...

Bevrani, Hassan (2004) Decentralized robust load-frequency control synthesis in restructured power systems. Preface This dissertation is mainly focused on technical issues associated with load-frequency control (LFC) in restructured power systems. Operating the power system in a deregulated environment is more complex than in the past, due to the considerable degree of interconnection and the p...