In many practical control problems the dynamics of the plant to be controlled are nonlinear. However, in most cases the controller design is based on a linear approximation of the dynamics. One of the reasons for this is that, in general, nonlinear control design methods are difficult to apply to practical problems. The State Dependent Riccati Equation (SDRE) control approach is a relatively ne...

In this report a number of algorithms for optimal control of a double inverted pendulum on a cart (DIPC) are investigated and compared. Modeling is based on Euler-Lagrange equations derived by specifying a Lagrangian, difference between kinetic and potential energy of the DIPC system. This results in a system of nonlinear differential equations consisting of three 2-nd order equations. This sys...

Purpose To evaluate long-term outcome of three years and treatment patterns of patients suffering from severely drug-refractory epilepsy (SDRE). Methods This analysis was population-based and retrospective, with data collected from four million individuals insured by statutory German health insurance. ICD-10 codes for epilepsy (G40*) and intake of anticonvulsants were used to identify prevale...

In this paper we present a method for optimal control of MIMO non-linear systems based on a combination of a neural network (NN) feedback controller and a state-dependent Riccati equation (SDRE) controller. Optimization of the NN is performed within a receding horizon model predictive control (MPC) framework, subject to dynamic and kinematic constraints. The SDRE controller augments the NN cont...

Site-directed RNA editing (SDRE) is a strategy to precisely alter genetic information within mRNAs. By linking the catalytic domain of the RNA editing enzyme ADAR to an antisense guide RNA, specific adenosines can be converted to inosines, biological mimics for guanosine. Previously, we showed that a genetically encoded iteration of SDRE could target adenosines expressed in human cells, but not...

Abstract We describe a computational technology for studying the effects of aerosol-radiation interaction and calculating regional estimates direct (DRE) semidirect radiative (SDRE) biomass burning (BB) aerosol based on simulations with CHIMERE chemistry transport model coupled WRF meteorological model. The was applied to numerical Siberian in eastern Arctic period July 16–31, 2016. show that s...

The continuous expansion of green finance makes it a new scheme to stimulate economic vitality, but its stimulation path remains be explored. Using the panel data 30 regions in China from 2016 2020, this research utilized an entropy method evaluate and sustainable development regional economy (SDRE), then discussed their coupling coordination relationship heterogeneity. results show that: (1) d...