OBJECTIVES Circulating 25-hydroxyvitamin D (25-OHD) is associated with improved cancer prognosis in some studies, yet it may be a surrogate marker for physical activity. We investigated the associations of leisure-time physical activity (LTPA) with circulating 25-OHD levels in cancer survivors, and determined whether associations differ by indoor and outdoor activity. DESIGN Cross-sectional s...

Optical heterodyne-detected Raman-induced Kerr optical activity (OHD-RIKOA) is a nonresonant ultrafast chiroptical technique for measuring the terahertz-frequency Raman spectrum of chirally active modes in liquids, solutions, and glasses of chiral molecules. OHD-RIKOA has the potential to provide much more information on the structure of molecules and the symmetries of librational and vibration...

30–35 ng/ml [6]. Priemel et al. [7], in their autopsy study, found that about 40% of bone samples from individuals with serum 25-OHD of 20–32 ng/ml still had elevated osteoid volumes typical for vitamin D deficiency. However, no osteomalacia was found in samples taken from individuals with serum levels higher than 32 ng/ml. In a meta-analysis, Bischoff-Ferrari and colleagues [8] showed that a s...

Fig. 1A. The Bland-Altman plot (Fig. 1B) confirmed this random tendency, which was independent of concentration and of sex, and also demonstrated an amplified dispersion at 25-OHD concentrations Ͼ50 nmol/L. Our data (Fig. 1B) suggested that CLIA results tended to be higher than RIA at low and high concentrations , conversely to data previously published (4). With a threshold of 25-OHD Ն30 nmol/...

Aims. This study aims at assessing the relationship between 25 (OH) vitamin D (25-OHD) levels and microvascular complications in patients with type 2 diabetes mellitus (DM2). Methods. 136 patients (59 ± 11 years) with DM2 (disease duration 8.6 ± 7 years) participated in this cross-sectional study. Anthropometric data, HbA1c, 25-OHD levels, serum creatinine, and urine microalbumin/creatinine rat...

Obesity is associated with alterations in the vitamin D endocrine system. Lower levels of serum 25-hydroxyvitamin D (25-OHD) in morbidly obese individuals may be secondary to an alteration in tissue distribution resulting from an increase in adipose mass. Therefore, morbidly obese individuals are expected to need higher doses of vitamin D supplementation than the general population. However, it...

Objective The spectrum of molecular defects in Chinese patients with 21-hydroxylase deficiency (21-OHD), and genotype-phenotype relationships are unknown. Methods We screened eight patients with non-classical (NC) 21-OHD and 35 with classical 21-OHD, and detected nine known mutations. Results The most frequent mutation among the 43 21-OHD cases was p.Ile172Asn (allele frequency, 36.0%), followe...

Eighty-six of 452 patients (19%) with chronic bifascicular block were found to have no clinically apparent associated organic heart disease (OHD) and were defined as having primary conduction disease (PCD). Comparison of patients with PCD and OHD revealed a significantly lower incidence of the following clinical variables in the PCD patients (p less than 0.001): exertional angina, dyspnea, cong...

Plasma 25-OHD levels were measured in the same 26 Caucasian women before pregnancy and during the first, second and third trimesters of their pregnancy. This was done to assess whether pregnancy alters vitamin D status in healthy women. During most times of the year there was no association between the 25-OHD levels and the stage of pregnancy, but between January and March there was a progressi...

Thirty-eight patients with collagen diseases undergoing chronic glucocorticoid treatment were studied to assess the effect of a 24 month administration of oral 1 alpha-hydroxyvitamin D (1 alpha-OHD), calcium and thiazide on bone and mineral metabolism. All patients were premenopausal women (mean age = 35 y.o.) and had been treated with prednisolone (mean dose = 11 mg/day). Patients were randoml...