نتایج جستجو برای: کشورهای mena
تعداد نتایج: 27993 فیلتر نتایج به سال:
UNLABELLED Fibronectin (FN) is a major component of the tumor microenvironment, but its role in promoting metastasis is incompletely understood. Here, we show that FN gradients elicit directional movement of breast cancer cells, in vitro and in vivo Haptotaxis on FN gradients requires direct interaction between α5β1 integrin and MENA, an actin regulator, and involves increases in focal complex ...
Drosophila Enabled is required for proper formation of axonal structures and is genetically implicated in signaling pathways mediated by Drosophila AbI. We have identified two murine proteins, Mena and Evl, that are highly related to Enabled as well as VASP (Vasodilator-Stimulated Phosphoprotein). A conserved domain targets Mena to localized proteins containing a specific proline-rich motif. Th...
در بسیاری از کشورهای جهان هر ساله میزان تمرکز بازارها در صنایع و مؤسسات مختلف اندازه‌گیری می‌شود که نتایج آن راهنمای دولت‌ها برای سیاست‌گذاری‌های اقتصادی و بقای رقابت است. در این پژوهش تأثیر یکی از مهم ترین عوامل نهادی یعنی ساختار بازار بر کارایی نظام بانکی کشورهای خاورمیانه و شمال آفریقا در طی سال های 1995-2008 مورد بررسی قرار می‌گیرد. این بررسی در ابتدا میزان کارایی نظام بانکی کشورها را با اس...
There has been an unprecedented trade liberalization which started in the mid1980s in a wide spectrum of developing countries. In the same period, there have also been considerable changes in the tax structures of countries. This paper uses panel data on 65 countries, including 16 Middle East and North Africa (MENA) countries, for the period 1980–1997 to examine how tax structures responded to ...
To overcome the limited immunogenicity of the meningococcal group A (MenA) polysaccharide (Ps) vaccine, the protein conjugation technology was applied to the development of MenAfriVac® (Serum Institute of India Ltd.). The MenA Ps is covalently conjugated to a protein, which acts as an immunologic carrier. MenAfriVac is a purified MenA polysaccharide tetanus toxoid (TT) conjugated vaccine (10 μg...
The objective of this paper is to situate the MENA area within the emerging markets universe. We first discuss the various components of market emergence and generate four bootstrapped indexes reflecting market size, market activity, market pricing and transparency. We then draw inter-regional and country-level comparisons using a probit model and a hierarchical cluster analysis. Our results su...
We have shown previously that distinct Mena isoforms are expressed in invasive and migratory tumor cells in vivo and that the invasion isoform (Mena(INV)) potentiates carcinoma cell metastasis in murine models of breast cancer. However, the specific step of metastatic progression affected by this isoform and the effects on metastasis of the Mena11a isoform, expressed in primary tumor cells, are...
A fluorescent-particle-based multiplex flow cytometric immunoassay (MIA) for the detection of serum immunoglobulin G (IgG) and two IgG subclasses, IgG1 and IgG2, specific for Neisseria meningitidis serogroup A (MenA) and C (MenC) polysaccharides (PS) was developed. The assay comprised three separate duplex assays, one for the detection of the IgG response to MenA and MenC PS, another for the de...
WASP- and Ena/VASP-family proteins have been reported to regulate the cortical actin cytoskeleton as downstream effectors of the Rho-family small G-proteins Rac and Cdc42, but their functions are little understood. We observed the localization of the WASP family proteins, N-WASP and WAVE, and the Ena/VASP family protein, Mena, in protruding lamellipodia. Rat fibroblast cell line 3Y1 protruded l...
Ena/vasodilator-stimulated phosphoprotein (VASP) proteins regulate the geometry of the actin cytoskeleton, thereby influencing cell morphology and motility. Analysis of invertebrate mutants implicates Ena/VASP function in several actin-dependent processes such as axon and dendritic guidance, cell migration, and dorsal closure. In vertebrates, genetic analysis of Ena/VASP function is hindered by...
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