نتایج جستجو برای: کشورهای mena

تعداد نتایج: 27993  

Journal: :Cancer discovery 2016
Madeleine J Oudin Oliver Jonas Tatsiana Kosciuk Liliane C Broye Bruna C Guido Jeff Wyckoff Daisy Riquelme John M Lamar Sreeja B Asokan Charlie Whittaker Duanduan Ma Robert Langer Michael J Cima Kari B Wisinski Richard O Hynes Douglas A Lauffenburger Patricia J Keely James E Bear Frank B Gertler

UNLABELLED Fibronectin (FN) is a major component of the tumor microenvironment, but its role in promoting metastasis is incompletely understood. Here, we show that FN gradients elicit directional movement of breast cancer cells, in vitro and in vivo Haptotaxis on FN gradients requires direct interaction between α5β1 integrin and MENA, an actin regulator, and involves increases in focal complex ...

Journal: :Cell 1996
Frank B Gertler Kirsten Niebuhr Matthias Reinhard Jürgen Wehland Philippe Soriano

Drosophila Enabled is required for proper formation of axonal structures and is genetically implicated in signaling pathways mediated by Drosophila AbI. We have identified two murine proteins, Mena and Evl, that are highly related to Enabled as well as VASP (Vasodilator-Stimulated Phosphoprotein). A conserved domain targets Mena to localized proteins containing a specific proline-rich motif. Th...

زینب شاعری سعید عیسی‌زاده

در بسیاری از کشورهای جهان هر ساله میزان تمرکز بازارها در صنایع و مؤسسات مختلف اندازه‌گیری می‌شود که نتایج آن راهنمای دولت‌ها برای سیاست‌گذاری‌های اقتصادی و بقای رقابت است. در این پژوهش تأثیر یکی از مهم ترین عوامل نهادی یعنی ساختار بازار بر کارایی نظام بانکی کشورهای خاورمیانه و شمال آفریقا در طی سال های 1995-2008 مورد بررسی قرار می‌گیرد. این بررسی در ابتدا میزان کارایی نظام بانکی کشورها را با اس...

2005
MEHMET SERKAN TOSUN Mehmet Serkan Tosun

There has been an unprecedented trade liberalization which started in the mid1980s in a wide spectrum of developing countries. In the same period, there have also been considerable changes in the tax structures of countries. This paper uses panel data on 65 countries, including 16 Middle East and North Africa (MENA) countries, for the period 1980–1997 to examine how tax structures responded to ...

2014

To overcome the limited immunogenicity of the meningococcal group A (MenA) polysaccharide (Ps) vaccine, the protein conjugation technology was applied to the development of MenAfriVac® (Serum Institute of India Ltd.). The MenA Ps is covalently conjugated to a protein, which acts as an immunologic carrier. MenAfriVac is a purified MenA polysaccharide tetanus toxoid (TT) conjugated vaccine (10 μg...

2006
Thomas Lagoarde-Segot Brian M. Lucey

The objective of this paper is to situate the MENA area within the emerging markets universe. We first discuss the various components of market emergence and generate four bootstrapped indexes reflecting market size, market activity, market pricing and transparency. We then draw inter-regional and country-level comparisons using a probit model and a hierarchical cluster analysis. Our results su...

Journal: :Journal of cell science 2011
Evanthia T Roussos Michele Balsamo Shannon K Alford Jeffrey B Wyckoff Bojana Gligorijevic Yarong Wang Maria Pozzuto Robert Stobezki Sumanta Goswami Jeffrey E Segall Douglas A Lauffenburger Anne R Bresnick Frank B Gertler John S Condeelis

We have shown previously that distinct Mena isoforms are expressed in invasive and migratory tumor cells in vivo and that the invasion isoform (Mena(INV)) potentiates carcinoma cell metastasis in murine models of breast cancer. However, the specific step of metastatic progression affected by this isoform and the effects on metastasis of the Mena11a isoform, expressed in primary tumor cells, are...

Journal: :Clinical and vaccine immunology : CVI 2008
Richarda M de Voer Fiona R M van der Klis Carla W A M Engels Ger T Rijkers Elisabeth A Sanders Guy A M Berbers

A fluorescent-particle-based multiplex flow cytometric immunoassay (MIA) for the detection of serum immunoglobulin G (IgG) and two IgG subclasses, IgG1 and IgG2, specific for Neisseria meningitidis serogroup A (MenA) and C (MenC) polysaccharides (PS) was developed. The assay comprised three separate duplex assays, one for the detection of the IgG response to MenA and MenC PS, another for the de...

Journal: :Journal of cell science 2001
H Nakagawa H Miki M Ito K Ohashi T Takenawa S Miyamoto

WASP- and Ena/VASP-family proteins have been reported to regulate the cortical actin cytoskeleton as downstream effectors of the Rho-family small G-proteins Rac and Cdc42, but their functions are little understood. We observed the localization of the WASP family proteins, N-WASP and WAVE, and the Ena/VASP family protein, Mena, in protruding lamellipodia. Rat fibroblast cell line 3Y1 protruded l...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2004
A Sheila Menzies Attila Aszodi Scott E Williams Alexander Pfeifer Ann M Wehman Keow Lin Goh Carol A Mason Reinhard Fassler Frank B Gertler

Ena/vasodilator-stimulated phosphoprotein (VASP) proteins regulate the geometry of the actin cytoskeleton, thereby influencing cell morphology and motility. Analysis of invertebrate mutants implicates Ena/VASP function in several actin-dependent processes such as axon and dendritic guidance, cell migration, and dorsal closure. In vertebrates, genetic analysis of Ena/VASP function is hindered by...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید