INTRODUCTION:  Novel semisolids are non greasy since they are made up of water washable bases. Hence they cause less irritation to skin and are superior to conventional semisolid dosage form.  Novel creams now a days are provided with nanoparticles and microspheres, which has an excellent emollient effect, with better spreadability, and less staining than oleaginous ointments. However both me...

OBJECTIVE To evaluate the efficacy and tolerability of 2 widely used topical alpha-hydroxy acids at low concentrations, 8% glycolic acid and 8% lactic (L-isoform) acid creams, in the treatment of photodamaged skin. DESIGN A single-center, 22-week, double-blind, vehicle-controlled, randomized clinical trial assessed the overall severity of photodamage on the faces and forearms of volunteers, b...

During the healing process of third-degree skin burns, a very complex response involves different cells and tissues linked together by intra- and extra-cellular mechanisms. For the restoration of damaged tissues, angiogenesis is the key point in the formation of new blood vessels. By their emollient, astringent, antiseptic, anti-inflammatory, biostimulator, epithelizing and cicatrizing effect, ...

The waterproofing effect of a number of creams, oils, and greases was examined by measuring water loss from adult skin before and after topical application. Creams had a high water content and were ineffective, oils produced a modest fall in water loss, but paraffin in grease form had a pronounced, sustained waterproofing effect. A paraffin mixture (80% soft, 20% hard paraffin (BP) was then app...

The aim of present study was to determine the antipsoriatic activity of newly formulated O/W creams of methanolic extract of Cassia tora L. leaves by using ultraviolet-B-induced psoriasis in rat. The plant Cassia tora L. is traditionally claimed to be useful in the treatment of a number of skin diseases. However, there are no established scientific reports for its antipsoriatic activity. Methan...