Antibiotic resistance genes (ARGs) pose a widespread concern for human health and wastewater treatment plants (WWTPs) are considered to be major source of ARG transmission. In this paper, the potential hosts genetic characteristics ARGs in influent, activated sludge effluent WWTPs Xinjiang were studied by metagenomics. Bacitracin gene (bacA), beta-lactamase (class A beta-lactamase), multidrug (...

AIMS This study was carried to reveal the genetic mechanisms of trimethoprim/sulfamethoxazole (SXT) resistance. METHODS Among 300 clinical Stenotrophomonas maltophilia isolates from China, resistance determinants such as sul and dfrA genes, integrons and transposase were examined using PCR, DNA sequencing and thermal asymmetric interlaced PCR (TAIL-PCR). Data were analyzed using SPSS 20.0. ...

Nan Ai1, Onejae Sul2, Milan Begliarbekov1, Qiang Song1, Kitu Kumar2, Daniel S. Choi3, Eui-Hyeok Yang2, and Stefan Strauf1 ∗ 1Department of Physics and Engineering Physics, Stevens Institute of Technology Castle Point on the Hudson, Hoboken, NJ 07030, USA 2Department of Mechanical Engineering, Stevens Institute of Technology Castle Point on the Hudson, Hoboken, NJ 07030, USA 3Department of Mater...

Despite of a high abundance antibiotics, heavy metals, and organic matters detected in the Saigon River Ho Chi Minh City, level spread antibiotic resistance genes this river are poorly understood. In study, total 10 (ARGs), including conferring to aminoglycosides (aac(6)-Ib-cr), β-lactam antibiotics (blaCTX-M, blaSHV, blaTEM), quinolones (qnrA, qnrB), sulfonamides (sul1, sul2), trimethoprim (df...

Emerging resistance to trimethoprim/sulfamethoxazole (SXT) poses a serious threat to the treatment of Stenotrophomonas maltophilia infections. We determined the prevalence and molecular characteristics of acquired SXT resistance in recent clinical S. maltophilia isolates obtained from Korea. A total of 252 clinical isolates of S. maltophilia were collected from 10 university hospitals in Korea ...

In this study, mechanisms of plasmid-mediated sulfamethoxazole resistances in the clinical strains of multi-drug resistant (MDR) Shigella flexneri 2a were elucidated for the first time in Bangladesh. From 2006 to 2011, a total of 200 S. flexneri 2a strains were randomly selected from the stock of the Enteric and Food Microbiology Laboratory of icddr,b. Antimicrobial susceptibility of the strain...

Klebsiella pneumoniae is one of the most important opportunistic enteric bacteria and is a major cause of pneumonia and urinary tract infection. Serotype capsules of K1 and K2 can cause intense diseases. Acquisition of plasmid that codes the production of ESBLs confers on K. pneumoniae resistance to number of broad spectrum antibiotics posing a global public health problem. Integron is one of t...

Sir, The Acinetobacter baumannii strain ATCC 17978 for which a genome sequence is available (GenBank accession number CP000521) was isolated in France in 1951, when antibiotic therapy was in its infancy. The sul1 sulphonamide resistance determinant and dfrA10 (dhfrX) trimethoprim resistance gene were reported to be present in this isolate. However, we were unable to find either gene in this gen...

BACKGROUND Assessment of resistance genes is imperative, as they become disseminated to bacterial flora in plants and to the indigenous bacterial community, and thus ultimately contributes to the clinical problems of antibiotic resistant pathogens. OBJECTIVES The research was to assess the antibiotic characteristics and incidence of sul3 genes of Stenotrophomonas maltophilia isolates recovere...

OBJECTIVES A florfenicol-resistant Pasteurella trehalosi isolate from a calf was investigated for the presence and the location of the gene floR. METHODS The P. trehalosi isolate 13698 was investigated for its in vitro susceptibility to antimicrobial agents and its plasmid content. A 14.9 kb plasmid, designated pCCK13698, was identified by transformation into Pasteurella multocida to mediate ...