By application of modern recombinant DNA technology, especially the polymerase chain reaction (PCR)/dot-blot hybridization techniques, we have investigated the molecular basis of β-thalassemia from four different regions of Iran: central, south-east, south and north. In this study, the DNA samples were isolated from patients and for the identification of the mutations, the 6 oligonucleotide...

Pulmonary hypertension (PH) is an important cause of heart failure in chronic obstructive pulmonary disease (COPD). The pro brain natriuretic peptide N-terminal (NT-proBNP) has been suggested as a noninvasive marker to evaluate ventricular function. However, there is no evidence to support the use of NT-proBNP in monitoring the benefits of vasodilators in COPD induced PH. Thus, we used NT-proBN...

A feeding trial has been conducted to evaluate the effects of dietary nucleotide (NT) on growth performance and stress resistance of fry kutum (Rutilus kutum Kamenskii, 1901). A basal diet supplemented with 0 (control), 0.3, 0.5 and 0.7 g NT kg-1 have been formulated for four experimental diets. After 8 weeks of feeding trial, growth parameters were evaluated and then fish has exposed to osmoti...

Pulmonary hypertension (PH) is an important cause of heart failure in chronic obstructive pulmonary disease (COPD). The pro brain natriuretic peptide N-terminal (NT-proBNP) has been suggested as a noninvasive marker to evaluate ventricular function. However, there is no evidence to support the use of NT-proBNP in monitoring the benefits of vasodilators in COPD induced PH. Thus, we used NT-proBN...

the effects of dietary nucleotide (nt) were evaluated on some serum biochemical parameters and acute stress responses of the catfish (pangasianodon hypophthalmus). five experimental diets including 0, 0.25, 0.5, 0.75, and 1% nt were supplied to catfish fry for 10 weeks. at the end of the experiment, fish fed the control and 1% nt diets were subjected to handling and crowding stress. the results...

the studies carried out over 2010-13 involved a static field experiment initiated in 1999 at brody research station of the poznan university of life science, poland. the soil tillage systems for winter wheat were compared on a soil classified as albic luvisols. the aim of experiments was to evaluate impact of ploughless soil tillage on some soil physical, chemical, biological properties and win...

1024x768 normal 0 false false false en-us x-none fa background : heart failure is a common health problem with poor prognosis. the gold standard for diagnosis is echocardiography but it is not always reachable, especially in emergency conditions. nt-pro-brain natriuretic peptide (nt-probnp) is a novel indicator for the diagnosis of heart failure and is being used in routine tests in emergency r...

RNAi mechanism plays a major role in silencing the expression of target genes by siRNAs. In the current study, in silico properties of 30 genes in omega-2 gliadin and 266 nt and 326 nt mutations were investigated before and after cloning in an expression vector. Specific primers were designed for 30 genes with spacer regions of 75 nt and 178 nt (for gene invert repeats). The frequency of siRNA ...