نتایج جستجو برای: ژن hlya

تعداد نتایج: 16132  

2015
Michael H. H. Lenders Stefanie Weidtkamp-Peters Diana Kleinschrodt Karl-Erich Jaeger Sander H. J. Smits Lutz Schmitt

Type 1 secretion systems (T1SS) of Gram-negative bacteria are responsible for the secretion of various proteases, lipases, S-layer proteins or toxins into the extracellular space. The paradigm of these systems is the hemolysin A (HlyA) T1SS of Escherichia coli. This multiple membrane protein complex is able to secrete the toxin HlyA in one step across both E. coli membranes. Common to all secre...

2015
Michael H. H. Lenders Stefanie Weidtkamp-Peters Diana Kleinschrodt Karl-Erich Jaeger Sander H. J. Smits Lutz Schmitt

Type 1 secretion systems (T1SS) of Gram-negative bacteria are responsible for the secretion of various proteases, lipases, S-layer proteins or toxins into the extracellular space. The paradigm of these systems is the hemolysin A (HlyA) T1SS of Escherichia coli. This multiple membrane protein complex is able to secrete the toxin HlyA in one step across both E. coli membranes. Common to all secre...

2011
T.K. Dutta P. Roychoudhury S. Bandyopadhyay S.A. Wani I. Hussain

BACKGROUND & OBJECTIVES Limited information is available on shiga toxin producing Escherichia coli (STEC) in animals and birds from India. An outbreak of acute diarrhoea in poultry birds at Aizawl, Mizoram was investigated for detection and characterization of STEC and enteropathogenic E. coli (EPEC). METHODS E. coli was isolated and identified from rectal swabs, intestinal contents, heart bl...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1993
F Zhang D I Greig V Ling

Secretion of the 107-kDa hemolysin A (HlyA) from Escherichia coli is mediated by the membrane proteins hemolysin B and hemolysin D. Hemolysin B is a member of the so-called ATP binding cassette transporter superfamily, which includes the multidrug resistance P-glycoprotein, the cystic fibrosis CFTR protein, and the major histocompatibility complex-associated transporter of antigenic peptides. R...

Journal: :Infection and immunity 2013
Amable J Rivas Miguel Balado Manuel L Lemos Carlos R Osorio

Photobacterium damselae subsp. damselae causes infections and fatal disease in marine animals and in humans. Highly hemolytic strains produce damselysin (Dly) and plasmid-encoded HlyA (HlyA(pl)). These hemolysins are encoded by plasmid pPHDD1 and contribute to hemolysis and virulence for fish and mice. In this study, we report that all the hemolytic strains produce a hitherto uncharacterized ch...

Journal: :FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006
Andreas Koschinski Holger Repp Baris Unver Florian Dreyer Dierk Brockmeier Angela Valeva Sucharit Bhakdi Iwan Walev

Escherichia coli alpha-hemolysin (HlyA), archetype of a bacterial pore-forming toxin, has been reported to deregulate physiological Ca2+ channels, thus inducing periodic low-frequency Ca2+ oscillations that trigger transcriptional processes in mammalian cells. The present study was undertaken to delineate the mechanisms underlying the Ca2+ oscillations. Patch-clamp experiments were combined wit...

Journal: :Microbiology and molecular biology reviews : MMBR 1998
P Stanley V Koronakis C Hughes

The pore-forming hemolysin (HlyA) of Escherichia coli represents a unique class of bacterial toxins that require a posttranslational modification for activity. The inactive protoxin pro-HlyA is activated intracellularly by amide linkage of fatty acids to two internal lysine residues 126 amino acids apart, directed by the cosynthesized HlyC protein with acyl carrier protein as the fatty acid don...

2017
M. Srivani Y. Narasimha Reddy K. V. Subramanyam M. Ramakoti Reddy T. Srinivasa Rao

AIM Aim of the study was to investigate the prevalence, virulence gene profiles, and antimicrobial resistance pattern of Shiga toxigenic Escherichia coli (STEC) in diarrheic buffalo calves from Andhra Pradesh and Telangana States. MATERIALS AND METHODS A total of 375 fecal samples from diarrheic buffalo calves of 1-7, 8-30, 31-60, and 61-90 days age were collected from which STEC were isolate...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه پیام نور - دانشگاه پیام نور استان تهران - دانشکده علوم پایه 1391

چکیده سابقه و هدف: لیستریا مونوسیتوژنز یک باکتری گرم مثبت، پاتوژن داخل سلولی اختیاری و علت وقوع مسمومیت های غذایی و همچنین عامل بیماری های شدید در گروه های آسیب پذیر جامعه انسانی می باشد. روش استاندارد برای تشخیص این باکتری کشت میکروبی بوده که این روش بیشتر از 36 ساعت طول می کشد. لذا دست یابی به آزمونی که بتواند در هر شرایطی وجود این باکتری را در نمونه بالینی نشان دهنده، ارزشمند است .لیستریوزی...

ژورنال: :مجله تحقیقات دامپزشکی (journal of veterinary research) 2011
مجتبی بنیادیان تقی زهرایی صالحی محمدرضا محزونیه فروغ اخوان طاهری

اشریشیاکلی وروتوکسیژن شامل سویه ها یی است که دارای ژن های1 stx و 2stx می باشند که هر کدام نقشی در بیماریزایی باکتری e. coli دارند. این سویه ها باعث بروز اسهال خونی، سندرم همولیتیک اورمیک و ترومبوسایتوپنی پورپورا می شود. از آنجایی که احتمال وجود باکتری e. coli و سویه های وروتوکسین زا در مواد غذایی گوناگون از جمله شیر و پنیر زیاد است و به لحاظ اهمیت زیاد این سویه ها در بهداشت انسان، در همین راستا...

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