We propose a method of inference for generalized linear mixed models Ž . GLMM that in many ways resembles the method of least squares. We also show that adequate inference about GLMM can be made based on the conditional likelihood on a subset of the random effects. One of the important features of our methods is that they rely on weak distributional assumptions about the random effects. The met...

OBJECTIVE Variability in infant sleep and negative affective behavior (NAB) is a developmental phenomenon that has long been of interest to researchers and clinicians. However, analyses and delineation of such temporal patterns were often limited to basic statistical approaches, which may prevent adequate identification of meaningful variation within these patterns. Modern statistical procedure...

In this talk, I will consider the generalized linear mixed models (GLMMs) with two components of dispersion. The frequentist analysis of GLMM is computationally di cult. On the other hand, the advent of the Markov chain Monte Carlo algorithm has made the Bayesian analysis of GLMM computationally convenient. I use recently proposed data cloning approach, which is computationally convenient, to c...

We find closed form expressions for the standardized cumulants of generalized linear models. This reduces the complexity of their calculation from O(p6) to O(p2) operations which allows efficient construction of second-order saddlepoint approximations to the pdf of sufficient statistics. We adapt the result to obtain a closed form expression for the second-order Laplace approximation for a GLMM...

background and aims: diabetes type ii (non-insulin dependent) which is one of the most prevalent diabetes types in the world emerges in people with the age of above 55 and genetic and environmental factors interfere in this disease. the aim of this study was to determine the factors affecting diabetes type ii with generalized mixed linear model. methods: population of this study included 2820 p...

BACKGROUND Focus groups, rapid assessment procedures, key informant interviews and institutional reviews of local health services provide valuable insights on health service resources and performance. A long-standing challenge of health planning is to combine this sort of qualitative evidence in a unified analysis with quantitative evidence from household surveys. A particular challenge in this...

The normal growth of mycobacteria attributes to the integrity of cell wall core which consists of peptidoglycan (PG), arabinogalactan (AG) and mycolic acids. N-acetyl glucosamine (GlcNAc) is an essential component in both PG and AG of mycobacterial cell wall. The biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc), as a sugar donor of GlcNAc, is different in prokaryotes and eukaryotes...

The ongoing Small Area Income and Poverty Estimates (SAIPE) project at the Census Bureau estimates numbers of poor school-age children by state, county, and ultimately school district, based upon Current Population Survey (CPS) and IRS data along with information from the latest decennial census. The current SAIPE county-level methodology relies on a Fay-Herriot (1979) model fitted to log-count...