Background: Liver cirrhosis is one of the most significant causes death in many regions worldwide. This study aimed to assess correlation hemostatic and endocrine parameters with Child-Turcotte-Pugh (CTP) scoring patients non-alcoholic liver cirrhosis. Materials Methods: included 59 monitored for a gastroenterology clinic from January 2018 February 2019. The subjects were grouped according CTP ...

Objective(s): to investigate the chronopharmacological effects of growth hormone on executive function and the oxidative stress response in rats. Materials and Methods: Fifty male Wistar rats (36-40 weeks old) had ad libitum access to water and food and were separated into four groups: diurnal control, nocturnal control, diurnal GH-treated, and nocturnal GH-treated animals. Levels of Cu, Zn sup...

The first successful treatment of growth hormone (GH) deficient children with GH extracted from human pituitary was introduced during late 1950's.  The subsequent availability and use of recombinant GH (rhGH) for different clinical conditions raised the question of whether this new therapeutic modality increases the risk of certain conditions such as leukemia or malignancy.  Herein, we report o...

The aim of this study was to investigate the potential association between growth hormone GH/AluI and growth hormone receptor GHR/AluI polymorphisms with milk yield and reproductive performances in Holstein dairy cows in Iran. Blood samples of 150 Holstein cows were collected and their genomic DNA was extracted using Gene-Fanavaran DNA extracting kit. Fragments of the 428 bp of exon 5 growth ho...

GH is involved in growth and development in vertebrates [1]. The actions of GH are initiated by its binding to the specific GH-receptors (GH-R) localized in the cell membrane of target tissues [2]. GH also binds to a soluble GH-binding protein (GH-BP) in serum [3]. The GH-BP is generated from a variant mRNA resulting from an alternative splicing of GH-R mRNA precursor at the exon 7-8 boundary [...

This study introduce a new type of closed sets in topology called Generalized h-closed (briefly, gh-closed) define as follow: E ⊆ χ be gh-closed set if CLh (E)⊆ U whenever and is open (χ,τ). The relation between other classes ( h-closed, g-closed, g -closed, g-closed αg-closed) are studied. Also, the notion gh-continuous mapping on topological space some properties proved. Finally, separation a...