The bodies of most teleost fish species are covered with specialized subepithelial structures known as scales. The scale is an epithelial appendage that differentiates from the dermal mesenchyme. Mammals, on the other hand, have no scales, but instead their bodies are covered with hair. Although their appearances are quite different, scales and hair can be considered structurally similar in tha...

Radiotherapy of head and neck cancers often results in collateral damage to adjacent salivary glands associated with clinically significant hyposalivation and xerostomia. Due to the reduced capacity of salivary glands to regenerate, hyposalivation is treated by substitution with artificial saliva, rather than through functional restoration of the glands. During embryogenesis, the ectodysplasin/...

PT Vale menerapkan sistem dumping tanpa mundur di Disposal Hasan sebagai upaya untuk mengurangi risiko kecelakaan kerja area disposal yang menyebabkan jarak dorong dozer D8R unit 4084 dan 4072 semakin jauh sehingga data waktu edar lama. Waktu lama mengakibatkan nilai produksi tidak optimal. Penelitian ini dilakukan menghitung aktual harian dari mengoptimasi pada masing-masing beroperasi dengan ...

NF-kappaB/Rel transcription factors and IkappaB kinases (IKK) are essential for inflammation and immune responses, but also for bone-morphogenesis, skin proliferation and differentiation. Determining their other functions has previously been impossible, owing to embryonic lethality of NF-kappaB/Rel or IKK-deficient animals. Using a gene targeting approach we have ubiquitously expressed an NF-ka...

Recent studies in Asian populations have identified variants in the EDAR and FGFR2 genes that arose following the divergence of Asians and Europeans and are associated with thick straight hair. To date no genetic variants have been identified influencing hair texture in Europeans. In the current study we examined the heritability of hair curliness in three unselected samples of predominantly Eu...

Ectodermal dysplasia (ED) is a group of syndromes characterized by abnormalities of structures of ectodermal origin. Up to now more than 150 different syndromes are known. Affected ectodermal structures are mainly hair, teeth, nails and sweat glands. ED can be classified by mode of inheritance (autosomal dominant, autosomal recessive and X-linked), by additional clinical symptoms (e.g. facial a...

One of the strongest signals of positive selection in humans surrounds the V370A variant of Ectodysplasin A receptor (EDAR). However, its phenotypic consequences and impetus for selection are not well understood. Kamberov et al. nail down when it originated and, using transgenic mice, delineate its phenotypic impacts.

AbstractEarly 2020, COVID-19 emerged in Indonesia and government declared it an emergency. So those efforts are needed to deal with by procuring medical devices through emergency procurement mechanism. In of devices, there technical specifications that must be met, is distribution permits. Due the limited number used for COVID-19, Minister Health provided relaxation form releasing permits, whic...

Penelitian ini bertujuan untuk memahami perlindungan konsumen terhadap produk kosmetik ilegal yang dijual secara bebas dan menganalisis pengawasan dilakukan oleh Badan Pengawas Obat Makanan (BPOM) impor tanpa izin edar, serta sanksi diberikan kepada pelaku usaha melakukan praktik tersebut. Metode penelitian digunakan adalah hukum normatif kepustakaan, dengan menggunakan data sumber seperti putu...

EDAR (event-driven assembler robot) — a mobile robot capable of moving a collection of disk-shaped parts located on a two-dimensional workspace from an arbitrary initial configuration to a desired configuration while avoiding collisions in a purely reactive manner, is presented. Since EDAR uses a higher-level scheduler to switch among the subtasks of moving individual parts, it is viewed as med...