نتایج جستجو برای: ژن blaz

تعداد نتایج: 15893  

Journal: :Applied and environmental microbiology 2004
Emmanuelle Charpentier Ana I Anton Peter Barry Berenice Alfonso Yuan Fang Richard P Novick

Our understanding of staphylococcal pathogenesis depends on reliable genetic tools for gene expression analysis and tracing of bacteria. Here, we have developed and evaluated a series of novel versatile Escherichia coli-staphylococcal shuttle vectors based on PCR-generated interchangeable cassettes. Advantages of our module system include the use of (i) staphylococcal low-copy-number, high-copy...

2014
Min-Hee Kang Min-Joo Chae Jang-Won Yoon Seung-Gon Kim So-Young Lee Jong-Hyun Yoo Hee-Myung Park

The prevalence, virulence potential, and antibiotic resistance of ophthalmic Staphylococcus pseudintermedius (SP) isolated from dogs were examined. Sixty-seven Staphylococcus species were isolated from ophthalmic samples and surveyed for species-specific sequences in the Staphylococcus intermedius group (SIG) nuclease gene (SInuc), exfoliative toxin gene for SIG (siet), and antibiotic resistanc...

2015
Radhwane SAIDI Zafer CANTEKİN Djamel KHELEF Yaşar ERGÜN Hasan SOLMAZ Rachid KAIDI

The study aimed to investigate the phenotypic and genotypic identification of in vitro antimicrobial susceptibility of 21 Staphylococci (10 Staphylococcus aureus and 11 Coagulase Negative Staphylococci) isolated from bovine mastitis to 12 antimicrobial drugs frequently using in veterinary medicine in Algeria. Isolates of staphylococci from bovine mastitis were tested for antibiotics with disc-d...

Journal: :Journal of infection in developing countries 2015
Mariela Elizabeth Srednik Mario Andres Grieben Adriana Bentancor Elida Raquel Gentilini

INTRODUCTION Bovine mastitis is a frequent cause of economic loss in dairy herds. Coagulase-negative staphylococci (CoNS) are increasing in importance as causeof bovine intramammary infection (IMI) throughout the world in recent years. CoNShave been isolated from milk samples collected from cows with clinical andsubclinical mastitis in several countries. Identification of mastitis pathogensis i...

Journal: :Antimicrobial agents and chemotherapy 2002
Takashi Ida Ryoichi Okamoto Masato Nonoyama Kazuhiko Irinoda Mizuyo Kurazono Matsuhisa Inoue

We encountered three clinical isolates of methicillin-resistant Staphylococcus aureus which were susceptible to netilmicin and arbekacin in the absence of beta-lactam antibiotics but which were resistant to them in the presence of beta-lactam antibiotics. One of these strains, KU5801, was used to further investigate the antagonism between aminoglycosides and beta-lactam antibiotics. beta-Lactam...

2017
Adriano Martison Ferreira Katheryne Benini Martins Vanessa Rocha da Silva Alessandro Lia Mondelli Maria de Lourdes Ribeiro de Souza da Cunha

Staphylococcus aureus and Staphylococcus saprophyticus are the most common and most important staphylococcal species associated with urinary tract infections. The objective of the present study was to compare and to evaluate the accuracy of four phenotypic methods for the detection of beta-lactamase production in Staphylococcus spp. Seventy-three strains produced a halo with a diameter ≤28mm (p...

Journal: :Journal of bacteriology 2001
B Fournier Q C Truong-Bolduc X Zhang D C Hooper

NorA, a multidrug efflux pump in Staphylococcus aureus, protects the cell from multiple drugs, including quinolones. The flqB mutation (T-->G) in the 5' untranslated region upstream of norA causes norA overexpression of 4.9-fold in cis, as measured in norA::blaZ fusions. The transcriptional initiation site of norA was unchanged in mutant and wild-type strains, but the half-life of norA mRNA was...

Journal: :Antimicrobial agents and chemotherapy 2013
Ewan M Harrison Gavin K Paterson Matthew T G Holden Fiona J E Morgan Anders Rhod Larsen Andreas Petersen Sabine Leroy Sarne De Vliegher Vincent Perreten Lawrence K Fox Theo J G M Lam Otlis C Sampimon Ruth N Zadoks Sharon J Peacock Julian Parkhill Mark A Holmes

Recently, a novel variant of mecA known as mecC (mecA(LGA251)) was identified in Staphylococcus aureus isolates from both humans and animals. In this study, we identified a Staphylococcus xylosus isolate that harbors a new allotype of the mecC gene, mecC1. Whole-genome sequencing revealed that mecC1 forms part of a class E mec complex (mecI-mecR1-mecC1-blaZ) located at the orfX locus as part of...

Journal: :Amyotrophic lateral sclerosis & frontotemporal degeneration 2017
Ammar Al-Chalabi Peter M Andersen Siddharthan Chandran Adriano Chio Philippe Corcia Philippe Couratier Olof Danielsson Mamede de Carvalho Claude Desnuelle Torsten Grehl Julian Grosskreutz Trygve Holmøy Caroline Ingre Merete Karlsborg Grethe Kleveland Jan Christoph Koch Blaz Koritnik Magdalena KuzmaKozakiewicz Hannu Laaksovirta Albert Ludolph Christopher McDermott Thomas Meyer Bernardo Mitre Ropero Jesus Mora Pardina Ingela Nygren Susanne Petri Mónica Povedano Panades Francois Salachas Pamela Shaw Vincenzo Silani Gert Staaf Kirsten Svenstrup Kevin Talbot Ole-Bjørn Tysnes Philip Van Damme Anneke van der Kooi Markus Weber Patrick Weydt Joachim Wolf Orla Hardiman Leonard H van den Berg

Ammar Al-Chalabi, Peter M. Andersen, Siddharthan Chandran, Adriano Chio, Philippe Corcia, Philippe Couratier, Olof Danielsson, Mamede de Carvalho, Claude Desnuelle, Torsten Grehl, Julian Grosskreutz, Trygve Holmøy, Caroline Ingre, Merete Karlsborg, Grethe Kleveland, Jan Christoph Koch, Blaz Koritnik, Magdalena KuzmaKozakiewicz, Hannu Laaksovirta, Albert Ludolph, Christopher McDermott, Thomas Me...

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