The gastric pathogen Helicobacter pylori harbors one Nudix hydrolase, NudA, that belongs to the nucleoside polyphosphate hydrolase subgroup. In this work, the enzymatic activity of purified recombinant NudA protein was analyzed on a number of nucleoside polyphosphates. This predicted 18.6-kDa protein preferably hydrolyzes diadenosine tetraphosphate, Ap(4)A at a k(cat) of 0.15 s(-1) and a K(m) o...

Wild animal hunters and photographers have long taken advantage of the attraction that catnip holds over members of the cat family, while domestic cat owners purchase dried catnip leaves for use as a rejuvenator and exerciser that will bring old cats to new life. Indeed, when cats have the leaves placed near them, they immediately approach, sniff, and shortly thereafter rub their faces into the...

Isolation and GC/MS quantitative determination of ursolic acid in the herb of Nepeta cataria var. citriodora have been performed. The content of this compound was in the range 0.95 ñ 1.30%. Daucosterol (βsitosterol 3-O-β-D-glucoside) was also isolated from the plant, in addition to small amounts of β-sitosterol, campesterol, α-amyrin and β-amyrin. The content and composition of essential oil in...

In this study, we aimed to determine chemical composition and antibacterial activities of Satureja hortensis and Calamintha nepeta against to 20 phytopathogenic bacteria causing serious crop loss. The essential oils of S. hortensis and C. nepeta were isolated by the hydrodistillation method and the chemical composition of the essential oils were analyzed by GC-MS. The antibacterial properties o...

Non-small cell lung cancer (NSCLC) is regarded as one of the major intractable diseases, which was cured mainly by chemotherapeutics in the clinical treatment at present. But it is still a vital mission for the current medical and researchers that hunting a natural medicine which have little side effects and high-efficiency against the NSCLC on account of the shortcomings on current drugs. Nepe...

Epilepsy is a neurological disorder characterized by unprovoked, recurring seizures that disrupts the nervous system and can cause mental and physical dysfunction. Based on the ethno pharmacological information of the plant, the methanolic and aqueous extracts of the flowers of Nepeta bractaeta was evaluated for its antiepileptic activity. The methanolic and aqueous extracts of the flowers of N...

The article provides an information about the finds of six adventitious plant species in Sverdlovsk Region, two them are new to flora region (Hesperis pycnotricha Borbás et Degen., Nepeta sibirica L.). Four (Lotus corniculatus L., Silene dichotoma Ehrh., Urtica cannabina Vicia amoena Fisch.) were previously known from 1–2 localities Region and rare not only region, but also adjacent territories...