Objectives: The aim of the present study was to investigate immunotoxic effect of safranal (SAF), a main component of Crocus sativus essential oil, using Balb/c mice. Materials and Methods: SAF was administered intraperitoneally at doses of 0.1, 0.5 and 1 ml/kg for 3 weeks. Hystopathological examination of spleen and bone marrow, cellularity of spleen, delayed type of hypersensitivity (DTH) res...

Background: Hydatid cyst is the larval stage of the tape worm parasite, Echinococcus granulosus. Human is infected by ingestion of parasite ova excreted in dog feces. The anticancer activity of different antigens of hydatid cyst has been reported in the previous works. In this research, the role of immune system in induction of this anticancer activity has been investigated.Materials and Method...

rubella or german measles is a mild contagious disease in non-pregnant women, but in pregnant affected mother’s possibility of fetus infection in the first twelve weeks of gestation is 80%. between 13-14 weeks of gestation is 54% and by the end of the second trimester is 25%. if fetus gets infected severe anomalies will progress. at present no vaccination against rubella is begin envisaged by t...

to evaluatethe effects of supplementing diets of growing japanese quails (n=450; 7 days old) with chromium (cr) yeast and / or mannan oligosaccharides (mos) on productive performance, carcass traits and the immune system are reported. diets were a basal diet (control) or the basal diet supplemented with 600 mg cr-yeast/kg (cr 1), 1200 mg cr-yeast/kg (cr 2), 1.0 g mos/kg, cr 1 + mos or cr 2 + mo...

background:class ii transactivator (ciita) is a dominanttranscriptional element, controlling numerous genes in theimmune system. ciita is expressed in a constitutive pattern inantigen presenting cells although its expression can occur inother cell types. since the revelation of ciita, there have beenconsiderable advances toward understanding its role as anactivator of mhc ii genes in humans and...

there are two different contradictory approach regarding the interaction of the state immunity and jus cogens. some jurist argue that jus cogens rules should prevail over other inconsistent ordinary rules of international law including state immunity. this argument therefore depends upon the existence of conflict between rules of jus cogens, and the rule of customary law which requires one stat...

background: endometriosis is a frequent gynecologic disease with a severe impact on the quality of life in the affected women; its pathogenesis is yet to be fully understood, with an altered immunity as a possible key factor. the present study aimed to investigate the serum anti-inflammatory cytokine profile in the patients with endometriosis compared with the healthy controls. materials and me...

abstract background and aims: medical students are exposed to various infectious diseases during their clinical training period, including measles and rubella. in iran, to control the outbreaks of measles and rubella a mass vaccination campaign was conducted on 2003. the present investigation evaluates immunity to measles and rubella in a group of babol medical students and determines the preva...

the aim of the present work was to determine whether the administration of melatonin or l­-tryptophan (a precursor of melatonin) affects the immune responses and performance of broilers during induced exposure to aflatoxins in feed. the study was conducted from 0-6 weeks comprising six dietary treatments in triplicate with10 chickens in each replicate. the diets were formulated to supply 23% cr...