We have previously shown that ~10% of all eukaryotic mRNAs contain potential programmed -1 ribosomal frameshifting (-1 PRF) signals and that some function as mRNA destabilizing elements through the Nonsense-Mediated mRNA Decay (NMD) pathway by directing translating ribosomes to premature termination codons. Here, the connection between -1 PRF, NMD and telomere end maintenance are explored. Func...

In tomato, resistance to Pseudomonas syringae pv. tomato (Pst) strains expressing the avirulence gene avrPto requires the presence of at least two host genes, designated Pto and Prf. Here we report that Prf encodes a protein with leucine-zipper, nucleotide-binding, and leucine-rich repeat motifs, as are found in a number of resistance gene products from other plants. prf mutant alleles (4) were...

INTRODUCTION Local anesthetic infusion techniques have been reported to reduce opiate requirements and pain scores following different kinds of surgery, including orthopedic surgery, inguinal hernia, and Cesarean surgery in women. METHODS PRF-108 and PRF-110 formulations were applied to the wound space in an incisional model in pigs to test the hypothesis that these formulations have better a...

Traditionally, modes of Message Authentication Codes(MAC) such as Cipher Block Chaining (CBC) are instantiated using block ciphers or keyed Pseudo Random Permutations(PRP). However, one can also use domain preserving keyed Pseudo Random Functions(PRF) to instantiate MAC modes. The very first security proof of CBC-MAC [BKR00], essentially modeled the PRP as a PRF. Until now very little work has ...

background whiplash patients regard cervicogenic headache (ceh) as the most burdensome symptom of their condition. sufferers experience a significant degree of disability from headache, associated neck pain and disability, and sleep disturbance. lateral c1/2 joint pulsed radiofrequency (prf) treatment has been shown to produce significant relief from headache in patients with ceh. objectives th...

BACKGROUND Choukroun's platelet-rich fibrin (PRF) is an autologous leukocyte- and platelet-rich fibrin biomaterial. The purpose of this study was to analyse the in vitro effects of PRF on human bone mesenchymal stem cells (BMSC), harvested in the oral cavity after preimplant endosteal stimulation. MATERIALS AND METHODS BMSCs from primary cultures were cultivated with or without a PRF membrane...

Objectives Palmar hyperhidrosis (PH) exhibits excessive and unpredictable sweating. The most effective treatment for permanent cure is the ablation of thoracic sympathetic ganglia innervating hands. However, sympathectomy of T2 sympathetic ganglion by clipping or cauterization causes irreversible nerve damage, and results in a compensatory hyperhidrosis (CH). We herein used the pulsed radiofreq...

conclusions a new approach to treat lumbar facet joint pain with prf is simple to perform and without serious complications. in view of the good long-lasting results obtained with the two reported cases, randomized control trials are necessary to validate this new approach. case presentation a 71-year-old patient presented because of persisting pain in the left gluteal region radiating to the l...

The high squint diving SAR is widely used to provide the information in advance. Large squint angle deduces the deeper coupling of range and azimuth of SAR echoes which makes SAR imaging more difficult. Especially, the large range migration of the deep couple heavily burdens the imaging processing time and storage units. The diving motion of platform worsens the situation. This paper proposes t...