as the middle-aged in the society as well as stress-induced cognitive disorders and dementia are increasing, sport is identified as a suitable solution to prevent disorders in central nervous system. the aim of the present study was to compare the effects of 8 weeks of strength and endurance training on bdnf. for this purpose, 150 male wistar rats participated in endurance training (running wit...

Brain-derived neurotrophic factor (BDNF) is known to play a role in experience-dependent plasticity of the developing visual cortex. For example, BDNF acutely enhances long-term potentiation and blocks long-term depression in the visual cortex of young rats. Such acute actions of BDNF suggested to be mediated mainly through presynaptic mechanisms. A chronic application of BDNF to the visual cor...

Brain-derived neurotrophic factor (BDNF) is known to play a role in experience-dependent plasticity of the developing visual cortex. For example, BDNF acutely enhances long-term potentiation and blocks long-term depression in the visual cortex of young rats. Such acute actions of BDNF suggested to be mediated mainly through presynaptic mechanisms. A chronic application of BDNF to the visual cor...

Introduction: Ramadhan fasting increases mental and physical health. The study aims to evaluate the effect of on fatigue, sleepiness, depression anxiety mood, quality life (QoL), Brain-derived neurotrophic factor (BDNF) serum level.
 Methods: Twenty participants are included in group (FG), nineteen non-fasting (NFG). Fatigue severity scales (FSS), fatigue VAS, Epworth sleepiness scale (ESS...

Abstract Background Obsessive–compulsive disorder (OCD) is usually associated with insight’s heterogeneity, and those poor insight showed lower BDNF cognitive deficiencies. The aim was to detect the relation between executive dysfunction BDNF. Materials methods Forty patients diagnosed OCD forty matched healthy controls. Also, both good groups (assessed by Brown Assessment of Belief Scale) were...

The odontoblastic differentiation of dental pulp stem cells (DPSCs) associated with caries injury happens in an inflammatory context. We recently demonstrated that there is a link between inflammation and tissue regeneration, identified via enhanced DPSC-mediated dentinogenesis vitro. Brain-derived neurotrophic factor (BDNF) nerve growth factor-related gene family molecule which functions throu...

brain derived neurotrophic factor (bdnf) is a neurotrophin acting at several levels in the brain. additionally, bdnf was shown to be responsible for the survival, maintenance and growth of neurons. also, bdnf plays an important role in synaptic plasticity and memory processes. in activity-dependent synaptic plasticity, bdnf enhances long-term potentiation (ltp) in the hippocampus but blocks the...

BACKGROUND The human Val66Met polymorphism in brain-derived neurotrophic factor (BDNF), a key factor in neuroplasticity, synaptic function, and cognition, has been implicated in the pathophysiology of neuropsychiatric and neurodegenerative disorders. BDNF is encoded by multiple transcripts with distinct regulation and localization, but the impact of the Val66Met polymorphism on BDNF regulation ...

Depression is a complex psychiatric disorder that significantly impacts millions of individuals worldwide. Despite advances in our understanding its neurobiological underpinnings, treatment options remain limited, and not all patients respond adequately to available therapies. Emerging evidence has implicated brain-derived neurotrophic factor (BDNF), critical regulator neuronal plasticity, the ...