NOAA thanks the Science Advisory Board (SAB) for its thoughtful review of and comments on NOAA's evolving Integrated Ecosystem Assessment (IEA) efforts. The group's interest in and support of NOAA's IEA program is appreciated and welcomed. The main recommendation of the SAB is that " NOAA develop guidance for scientists, managers and their partners to develop timely and effective IEAs ". NOAA w...

BACKGROUND Interstitial eosinophilic aggregates (IEA) in renal biopsies often suggest allergic tubulointerstitial nephritis, yet clear associations with drug reactions are often difficult to establish. IEA are also encountered in diabetic nephropathy (DN) and thought to be attributed to medication exposure. METHODS Native medical kidney biopsies performed at the University of Washington Medic...

In this paper, the dynamic behavior of square plates with various thicknesses and stiffening configurations subjected to underwater explosion (UNDEX) are evaluated through a relatively novel approach which is called Incremental Explosive Analysis (IEA). The IEA estimates the different limit-states and deterministic assessment of plats’ behavior, considering uncertainty of loading conditions and...

A layer-encoded interactive evolutionary algorithm (IEA) for optimization of design parameters of a monolithic microwave integrated circuit (MMIC) low noise amplifier is presented. The IEA comprises a combination of the genetic algorithm (GA) and the particle swarm optimization (PSO) technique. The layer-encoding structure allows human intervention in order to accelerate the process of evolutio...

In skeletal muscle, an increased expression of insulin like growth factor-I isoforms IGF-IEa and mechano-growth factor (MGF) combined with downregulation of myostatin is thought to be essential for training-induced hypertrophy. However, the specific effects of different contraction types on regulation of these factors in muscle are still unclear, and in tendon the functions of myostatin, IGF-IE...