نتایج جستجو برای: پراکسیداز pox

تعداد نتایج: 4978  

چکیده به منظور بررسی فعالیت آنتی­اکسیدانی در ارقام گلابی درگزی و ویلیام دوشس بعد از مایه­زنی با باکتری مولد بیماری آتشک (E. amylovora)، آزمایشی به صورت فاکتوریل در قالب طرح بلوک­های کامل تصادفی در سه تکرار انجام شد. ارزیابی مقاومت بر اساس درصد نسبت پیشرفت بیماری آتشک در شاخه به کل طول شاخه صورت گرفت. برخی از شاخص­های فیزیولوژیکی و بیوشیمیایی شامل آنزیم­های آسکوربات پراکسیداز (APX)، کاتالاز (CA...

2012
Becki Lawson Shelly Lachish Katie M. Colvile Chris Durrant Kirsi M. Peck Mike P. Toms Ben C. Sheldon Andrew A. Cunningham

Avian pox is a viral disease with a wide host range. In Great Britain, avian pox in birds of the Paridae family was first diagnosed in a great tit (Parus major) from south-east England in 2006. An increasing number of avian pox incidents in Paridae have been reported each year since, indicative of an emergent infection. Here, we utilise a database of opportunistic reports of garden bird mortali...

2018
Ilona Zareba Katarzyna Celinska-Janowicz Arkadiusz Surazynski Wojciech Miltyk Jerzy Palka

Proline degradation by proline dehydrogenase/proline oxidase (PRODH/POX) contributes to apoptosis or autophagy. The identification of specific pathway of apoptosis/survival regulation is the aim of this study. We generated knocked-down PRODH/POX MCF-7 breast cancer cells (MCF-7shPRODH/POX). PRODH/POX silencing did not affect cell viability. However, it contributed to decrease in DNA and collage...

هدف این مطالعه ارزیابی اثر تنش شوری بر فعالیت ایزوزیم‌های آنتی‌اکسیدان سوپراکسید‌دیسموتاز (SOD)، کاتالاز (CAT) و پراکسیداز (POX) در 18 ژنوتیپ لوبیا سفید (Phaseolusvulgaris L.) و مقایسه با شرایط طبیعی در قالب فاکتوریل با طرح پایۀ کاملاً تصادفی است. برای هر نوار ژل فعالیت ایزوزیمی با نرم‌افزار MCID به‌صورت میزان ”مساحت × شدت“ محاسبه شد. سه ایزوزیم برای SOD، یک ایزوزیم برای CAT و سه ایزوزیم برای PO...

2012
Wei Liu Kristine Glunde Zaver M. Bhujwalla Venu Raman Anit Sharma James M. Phang

Proline is a readily released stress substrate that can bemetabolized by proline oxidase (POX) to generate either reactive oxygen species (ROS) to induce apoptosis or autophagy or ATP during times of nutrient stress. However, the contribution of prolinemetabolism to tumorigenesis in hypoxicmicroenvironments has not been explored. In this study, we investigated the different functions of POX und...

2010
Olga Zabirnyk Wei Liu Shadi Khalil Anit Sharma James M. Phang

Epidemiological studies showed that high levels of oxidized low-density lipoproteins (oxLDLs) are associated with increased cancer risk. We examined the direct effect of physiologic concentrations oxLDL on cancer cells. OxLDLs were cytotoxic and activate both apoptosis and autophagy. OxLDLs have ligands for peroxisome proliferator-activated receptor gamma and upregulated proline oxidase (POX) t...

2012
Meseko Clement Adebajo Shittu Ismail Ademola Akinyede Oluwaseun

Fowl pox is a viral disease of domestic and wild birds. The large size of the genome makes it a useful vector for recombinant DNA technology. Although the disease has been described in both commercial and indigenous chickens in Nigeria, data are limited on seroprevalence in free range chickens. Such data are, however, important in the design and implementation of fowl pox virus vector vaccine. ...

2009
George Jiang Meng Shi Solomon Conteh Nancy Richie Glenna Banania Harini Geneshan Anais Valencia Priti Singh Joao Aguiar Keith Limbach Kurt I. Kamrud Jonathan Rayner Jonathan Smith Joseph T. Bruder C. Richter King Takafumi Tsuboi Satoru Takeo Yaeta Endo Denise L. Doolan Thomas L. Richie Walter R. Weiss

Using newer vaccine platforms which have been effective against malaria in rodent models, we tested five immunization regimens against Plasmodium knowlesi in rhesus monkeys. All vaccines included the same four P. knowlesi antigens: the pre-erythrocytic antigens CSP, SSP2, and erythrocytic antigens AMA1, MSP1. We used four vaccine platforms for prime or boost vaccinations: plasmids (DNA), alphav...

2005
IAN S. PEARSE KATY D. HEATH JOHN M. CHEESEMAN

This study examines phenolic peroxidase (POX) in Rhizophora mangle L. leaves in order to assess its role in phenolic manipulation and H 2 O 2 scavenging. Sun-exposed and understorey leaves experiencing varying degrees of nutrient stress were analysed from an oligotrophic cay off the coast of Belize. POX activity was unaffected by growth environment, but increased throughout leaf development and...

Journal: :Cancer research 2001
S P Donald X Y Sun C A Hu J Yu J M Mei D Valle J M Phang

The p53-dependent initiation of apoptosis is accompanied by the induction of proline oxidase (POX), a mitochondrial enzyme catalyzing the conversion of proline to pyrroline-5-carboxylate with the concomitant transfer of electrons to cytochrome c. However, the contribution of increased POX activity to apoptosis, if any, remains unknown. Using Adriamycin to initiate p53-dependent apoptosis, we sh...

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