We studied the response to aldosterone, 11-deoxycorticosterone, 11-deoxycortisol, cortisol, corticosterone, progesterone, 19-norprogesterone and spironolactone of human, chicken, alligator, frog and zebrafish full-length mineralocorticoid receptors (MRs) and truncated MRs, lacking the N-terminal domain (NTD) and DNA-binding domain (DBD), in which the hinge domain and ligand binding domain (LBD)...

There have been many productive methods developed so far for optimization of multiple response surface (MRS) problems. This paper tends to review the most seminal approaches in MRS and discuss the strength and weakness of each of the approaches through existing aspects in MRS. A numerical example is included to compare results by different methods. Finally some of the prominent areas for future...

The macro-regional strategy (MRS) of the European Union (EU) is widely acknowledged as a soft form governance. To this view, identified macro-regions (MRs) are loosely demarcated regions, governance which hinges on informal coordination and flexible involvement actors. However, it also stated that MRs have potential to solidify. Nevertheless, how solidification may be handled in integrity has n...

An essay in which Warner speculates on the character and circumstances of William Hazlitt’s wife Sarah (née Stoddart) during stay Scotland from April to June 1822 was necessary for their divorce be concluded. draws Sarah’s Journal her travels Scotland.