هدف: کارآفرینی یکی از عوامل کلیدی در توسعه اقتصادی و شاخص اساسی جوامع روبه‌رشد است. آنچه که کارآفرین را به آغاز فعالیت ترغیب می‌کند، انگیزه فرایند تبدیل یک فرد عادی است می‌تواند فرصت‌هایی ایجاد کند حداکثر رساندن ثروت کمک کند. هدف این پژوهش شناسایی طبقه‌بندی انگیزه‌های کارآفرینان می­باشد.طراحی/ روش‌شناسی/ رویکرد: با رویکرد مرور نظام­مند استفاده ماتریس شش سلولی دو مؤلفه جهت (کشش یا فشار) منبع (اق...

Background Aicardi-Goutières syndrome (AGS) is a genetic disease, characterized by encephalopathy with cerebral calcification, white matter abnormalities, cerebral atrophy, elevated interferon-alpha in the cerebrospinal fluid and chilblain. Most of AGS patients have severe neurological findings including developmental delay. Five genes, namely TREX1, RNASEH2B, RNASEH2C, RNASEH2A, SAMHD1 have be...

هدف: هدف از پژوهش حاضر مقایسۀ واکنش ­پذیری هیجانی و نظریه ذهن کودکان بر اساس سبک ­های ابرازگری مادرانشان بود. روش: روش توصیفی نوع علّی-مقایسه­ ای بود در دو گام به صورت آنلاین انجام رسید. ابتدا با استفاده نمونه ­گیری دسترس، تعداد 105 نفر مادرانی که نمرات آن­ها هر یک پرسشنامه کینگ امونز (1990)، دوسوگرایی (1990) کنترل راجر نشوور (1987) انحراف استاندارد بالاتر میانگین دست آمد (در گروه 35 نفر) دوم وا...

Aicardi-Goutières syndrome (AGS) is a severe childhood inflammatory disorder that shows clinical and genetic overlap with systemic lupus erythematosus (SLE). AGS is thought to arise from the accumulation of incompletely metabolized endogenous nucleic acid species owing to mutations in nucleic acid-degrading enzymes TREX1 (AGS1), RNase H2 (AGS2, 3 and 4), and SAMHD1 (AGS5). However, the identity...

Comparative study of alloimmune responses against major and minor histocompatibility Ags has been limited by the lack of suitable assays. Here, we use a bioassay that permits tracking of alloreactive CD4+ T cell populations as they proliferate in response to major or minor histocompatibility Ags in vivo. Division of alloreactive CD4+ T cells proceeded more rapidly in response to major histocomp...

A sequencing batch reactor (SBR) inoculated with activated sludge and bioaugmented a dye-decolorizing yeast strain—Yarrowia lipolytica (HOMOGST27AB) was assembled to form yeast-bioaugmented aerobic granular (AGS). The AGS-SBR operated for the treatment of synthetic saline wastewater (12 g L−1) intermittently fed reactive textile dye (Navy Everzol ED) at 25, 15, 7.5 mg L−1. Dye degradation did n...

runx3, a member of runt-related transcription factor (runx) proteins with tumor suppressor effect, is a tissue–restricted and cancer related transcription factor that regulate cell proliferation and growth, as well as differentiation. in the present study, exogenous run3 was transiently expressed in ags (human gastric adenocarcinoma), with undetectable runx3 protein and in a549 (human lung carc...

We investigated the inhibition of apoptosis and proliferation of poorly differentiated AGS gastric cancer cells by epigallocatechin-3-gallate (EGCG), to establish target genes for regulation by EGCG. The proliferation and apoptosis of AGS gastric cancer cells treated with EGCG were observed by cell counting kit (CCK)-8 and flow cytometry. Differential gene expression in AGS cells treated with E...

Arctic Ground Squirrels (AGS) are classic hibernators known for their tolerance to hypoxia. AGS have been studied as a model of hypoxia with potential as a medical research model. Problem statement: Their unique resistance to the stressors of low oxygen led us to hypothesize that AGS might also be adaptable to hyperoxia. Approach: This study examined the physiological pattern associated with hy...

After the successfull completion of the AGS Booster and several upgrades of the AGS, a new intensity record of 6:3 10 13 protons per pulse accelerated to 24 GeV was achieved. Futher intensity upgrades are being discussed that could increase the average delivered beam intensity by up to a factor of six. The total beam power then reaches almost 1 M W and the AGS can then be considered as a proton...