PURPOSE To assess the safety and effectiveness of the MDT-2113 (IN.PACT Admiral) drug-coated balloon (DCB) for the treatment of de novo and native artery restenotic lesions in the superficial femoral and proximal popliteal arteries vs percutaneous transluminal angioplasty (PTA) with an uncoated balloon in a Japanese cohort. METHODS MDT-2113 SFA Japan ( ClinicalTrials.gov identifier NCT0194747...

BACKGROUND In severe injuries with loss of tendon substance a tendon graft or a synthetic substitute is usually used to restore functional length. This is usually associated with donor site morbidity, host tissue reactions and lack of remodelling of the synthetic substitutes, which may result in suboptimal outcome. A biocompatible graft with mechanical and structural properties that replicate t...

Cellulose is an important component of cell wall, yet its location and function in pollen tubes remain speculative. In this paper, we studied the role of cellulose synthesis in pollen tube elongation in Pinus bungeana Zucc. by using the specific inhibitor, 2, 6-dichlorobenzonitrile (DCB). In the presence of DCB, the growth rate and morphology of pollen tubes were distinctly changed. The organiz...

2015 Despite initially encouraging technical success after femoropopliteal percutaneous transluminal angioplasty (PTA), postprocedural restenosis remains the major challenge. Antiproliferative drugs applied via drug-coated balloons (DCBs) or drug-eluting stents suppress neointimal hyperplasia, the main cause of restenosis. The present article summarizes results of DCB treatments of femoropoplit...

We here describe that soluble HLA-DQ2 (sDQ2)molecules, when expressed in Drosophila melanogaster S2insect cells without a covalently tethered peptide, associatetightly with the D. melanogaster calcium binding proteinDCB-45. The interaction between the proteins is stable in S2cell culture and during affinity purification, which is done athigh salt concentrations and pH 11...

Mathematical models, for the stress analysis of symmetric multidirectional double cantilever beam DCB specimen using classical beam theory, first and higher-order shear deformation beam theories, have been developed to determine the Mode I strain energy release rate SERR for symmetric multidirectional composites. The SERR has been calculated using the compliance approach. In the present study, ...

We present quad-constellation (namely, GPS, GLONASS, BeiDou and Galileo) time group delay (TGD) and differential code bias (DCB) correction models to fully exploit the code observations of all the four global navigation satellite systems (GNSSs) for navigation and positioning. The relationship between TGDs and DCBs for multi-GNSS is clearly figured out, and the equivalence of TGD and DCB correc...

Tylophorine and its analogs are phenanthroindolizidine alkaloids, several of which have been isolated from the Tylophora genus of plants. Evaluation of ( )-S-tylophorine [DCB-3500 (NSC-717335)] and its analog DCB-3503 (NSC-716802) in the National Cancer Institute tumor screen showed a fairly uniform and potent inhibition of cell growth in all 60 cell lines (GI50 10 8 M). To further evaluate the...

Differential code biases (DCBs) are important parameters in GNSS (Global Navigation Satellite System) applications such as positioning as well as ionosphere remote sensing. In comparison to the conventional approach, which utilizes ground-based observations and parameterizes global ionosphere maps together with DCBs, a method is presented for GPS and BeiDou system (BDS) satellite DCB estimation...