OBJECTIVE To determine if cardiopulmonary bypass (CPB), together with inhibition of the sodium-hydrogen exchanger (NHE), limits myocardial and neurological injury and improves recovery after prolonged (unwitnessed) cardiac arrest (CA), as NHE inhibition improved recovery after deep hypothermic circulatory arrest. METHODS Twenty-seven pigs (31-39 kg) underwent 15 min of prolonged (no-flow) CA ...

To test the hypothesis that bradykinin effects cutaneous active vasodilation during hyperthermia, we examined whether the increase in skin blood flow (SkBF) during heat stress was affected by blockade of bradykinin B(2) receptors with the receptor antagonist HOE-140. Two adjacent sites on the forearm were instrumented with intradermal microdialysis probes for local delivery of drugs in eight he...

BACKGROUND Angiotensin-converting enzyme (ACE) inhibition potentiates the tissue-type plasminogen activator (t-PA) response to exogenous bradykinin. This study tested the hypothesis that ACE inhibition increases endothelial t-PA release through endogenous bradykinin. METHODS AND RESULTS We measured the effect of intra-arterial enalaprilat (5 micro g/min) on forearm blood flow (FBF) and net t-...

Samenvatting Ondanks overweldigend wetenschappelijk bewijs zijn we het niet allemaal eens over de feiten met betrekking tot een aantal belangrijke onderwerpen. Hoe kan dat? Dit artikel geeft overzicht van onderzoek naar hoe mensen vasthouden aan onjuiste overtuigingen terwijl ze geconfronteerd worden juiste informatie en wetenschapscommunicatie verbeterd om te helpen accurate komen.

We proposed an aerial projection 3D display based on integral imaging. It is composed of a projector, lens-array holographic optical element (HOE), and two parabolic mirrors. The HOE diffraction grating made by the volume holography technique. can be produced thin glass plate, it has properties lens array when Bragg condition satisfied. When beams image (EIA) are projected HOE, images reconstru...

BACKGROUND To evaluate the effect of bradykinin (BK) on TGF-β1-induced retinal pigment epithelial (RPE) cell proliferation and extracellular matrix secretion and to elucidate the relationship between BK and the Erk/Akt signaling pathway. METHODS The effects of BK on TGF-β1-induced RPE cell proliferation were examined via CCK-8 assay. Cell culture supernatant collagen I concentrations were mea...

A number of methods for producing holographic optical elements (HOEs) for use in projecting integral images in holographic stereogram printers are presented, with emphasis on application to Ultragram format one-step stereograms. Creation of HOEs to replace standard diffusion screens and enhance stereogram printer imaging properties and efficiency is discussed. Monolithic and integral holographi...

In this paper we study some of the arithmetic structure that is found in a special kind of semi-ring in the isols. These are the semi-rings [D(Y ),+, ·] that were introduced by J.C.E. Dekker, and that were later shown by E. Ellentuck to model the true universal recursive statements of arithmetic when Y is a regressive isol and is hyper-torre (= hereditarily odd-even = HOE). When Y is regressive...