Background and Amis: Serological assay is considered as one of the best choices for conducting large number of infection tests. Recombinant DNA technology has been used for expression of virus coat protein (CP) gene in prokaryotic bacterial cells such as Escherichia coli and the recombinant CP (rCP) is used as immunogen in antibody production. Heterologous CP protein expression and purification...

Fifteen healthy male volunteers (in four groups) received single 1 h i.v. infusions of alatrofloxacin (CP-116,517) equivalent to 30, 100, 200 or 300 mg of its active metabolite, trovafloxacin (CP-99,219). Blood and urine were sampled over 73 and 72 h, respectively, and plasma levels of alatrofloxacin and serum concentrations of trovafloxacin were determined by HPLC with UV detection. Alatroflox...

Background and purpose: The 2-chlorophenol (2-CP) and 4-chlorophenol (4-CP) are phenolic compounds which may have adverse effects on human and environment. Therefore, removing these compounds from water and wastewater is necessary. This study aims to analyze 2-CP and 4-CP removal by using Azolla filiculoides biomass. Materials & Methods: Azolla biomass was sun dried, crushed and sieved to parti...

In the present study, we aimed to address the use of ethyl pyruvate (EP) against the harmful effects of cyclophosphamide (CP) treatment. Thirty-nine adult male mice were divided into three groups including control group received normal saline [0.20 mL per day; intraperitoneally (IP)], CP group received CP (15.00 mg kg-1 per week, IP) and CP+EP group received EP (40.00 mg kg-1</s...

We have developed a new method for determination of serum ceruloplasmin from its oxidase activity, in which o-dianisidine dihydrochioride is used as substrate. o-Dianisidine dihydrochloride is more stable than is the more widely used p-phenylenediamine substrate, and forms a stable product that is measured at 540 nm. Correlation was good between results of this method and those obtained with bo...

conclusions oral mg supplementation did not protect the cp induced nephrotoxicity in diabetic rats. results cp administration in normoglycemic rats significantly elevated the serum levels of blood urea nitrogen (bun) and creatinine (cr) (p < 0.05). however, coadministration of cp and mg statistically increased the serum levels of bun and cr in both normoglycemic and diabetic animals when compar...