When newly hatched Caenorhabditis elegans larvae are starved, their primordial germ cells (PGCs) arrest in the post-S phase. This starvation-induced PGC arrest is mediated by the DAF-18/PTEN-AKT-1/PKB nutrient-sensing pathway. Here, we report that the conserved spindle assembly checkpoint (SAC) component MDF-1/MAD1 is required for the PGC arrest. We identified 2 Akt kinase phosphorylation sites...

The muscle-derived differentiation factor called MDF initiated expression of the catecholamine (CA) enzyme tyrosine hydroxylase (TH) in non-CA neurons isolated from a variety of regions in the rat brain. Specifically, subpopulations of neurons from the striatum, collicular plate, and cerebellum were TH-immunoreactive after an overnight exposure to MDF in culture. The number of immunopositive ce...

The goal of this study was to determine the comparative properties of dry-formed medium density fiberboards (MDF) made from renewable biomass (wheat and soybean straw) and those from conventional soft wood fiber. The MDF properties evaluated were modulus of elasticity, modulus of rupture, internal bond strength, thickness swell, and screw holding capacity. The results show that MDF made from wh...

The study aimed to investigate factors associated with respiratory symptoms in workers in a medium-density fiberboard (MDF) furniture factory in Eastern Thailand. Data were collected from 439 employees exposed to formaldehyde and MDF dust using questionnaire and personal sampler (Institute of Occupational Medicine; IOM). The average concentration of formaldehyde from MDF dust was 2.62 ppm (SD 3...

Crypt foci with absent or scant mucous production (mucin-depleted foci, MDF) were recently described by our group in the colon of azoxymethane (AOM)-treated rats. Since MDF are dysplastic and easy to quantify, we think that MDF are pre-neoplastic lesions that could be used as biomarkers for carcinogenesis. To test this hypothesis, we studied MDF in azoxymethane (AOM)-initiated rats treated with...

An accurate and efficient algorithm, closely related to the level set method, is presented for the simulation of Mullins’s model of grain growth with arbitrarily prescribed surface energies. The implicit representation of interfaces allows for seamless transitions through topological changes. Well-resolved large-scale simulations are presented, beginning with over 650,000 grains in two dimensio...

As opposed to “big data” as a buzz word, we attempt to find a new pattern or structure generated by selforganization in the flow of the massive data. We call this approach Massive Data Flows (MDF). Rather than making use of big data, we are interested in the new phenomena and theory that allows us to deal with the data without losing the autonomy, complexity, dynamics and structure that the dat...

OBJECTIVE To compare cycle outcomes among normal-responding patients <or=30 years old receiving microdose follicular flare (MDF) and long-luteal agonist (LL). DESIGN Retrospective cohort study. SETTING Military-based assisted reproductive technology (ART) center. PATIENT(S) First autologous ART cycles among 499 women <or=30 years old from January 1999 to December 2005. INTERVENTION(S) A...

SARNA, S. K., AND E. E. DANIEL. Electrical stimulation of gastric electrical control activity. Am. J. Physiol. 225(l): 125-131. 1973.Gastric electrical control activity in anesthetized dogs was stimulated by voltage pulses of 100 msec duration and lto 25-v amplitude. The gastric control waves could be entrained from any site in the electrically active region on the anterior and posterior sides....