Mr. Editor: It has been only recently possible to validate the Maslach Burnout Inventory-Human Services Survey (MBI-HSS) 1 among health professionals of Cali 2 , an important step for using this instrument with local empirical support in regard to its reliability of scoring and internal structure. However, two aspects of this analysis can be considered as methodological weaknesses. First, the C...

Most organizations today operate in a highly complex and competitive business environment and need to be able to react to rapidly changing market conditions. IT management frameworks are widely used to provide effective support for business objectives through aligning IT with business and optimizing the use of IT resources. In this paper we analyze three IT management frameworks (ITIL, COBIT an...

The objective of this study is to assess the association between levels of empathy and burnout of emergency professionals in all the assistance levels.A cross-sectional observational study was conducted in the health region of Lleida and the Pyrenees with 100 professionals from the field of Urgency. Participation reached 40.8%. Empathy and burnout were measured using the Spanish versions of the...

OBJECTIVES To investigate the Maslach Burnout Inventory-General Survey (MBI-GS) and the Utrecht Work Engagement Scale (UWES) for their ability to identify non-sicklisted employees at increased risk of long-term sickness absence (LTSA). METHODS One-year prospective cohort study including 4,921 employees participating in occupational health surveys in the period 2008-2010. The MBI-GS and UWES w...

This paper concentrates on two key areas connected with business informatics, i.e., business informatics management and the role of ICT in promoting sustainable development. The surveys mentioned in this paper show that organisations in the Czech Republic do not devote sufficient attention to these areas and thus lag behind organisations in other developed countries. To help enterprises with th...

The dimensional structure of the Maslach Burnout Inventory-Student Survey (MBI-SS) was investigated using data collected from three samples of Chinese students in two high schools, a university, and a nursing school, respectively (total N = 1,499; 36% males, 64% females; M age 19.0 yr., SD = 1.3). Single group Confirmatory Factor Analyses corroborated the hypothesized three-factor model for the...

During a 17-year period (1966-1983), 519 patients received renal allografts at the Johannesburg Hospital. Ten patients developed mycobacterial infections (MBI) in their post-transplant perio4 — a prevalence of 1,7%. Eight were dueto Mycobacteriumtuberculosis (M. tuberculosis); of the remaining two, one was due to Mycobacterium kansasii and one to MycobacteriunT forthuitum. Two patients died as ...

Inhibition of cytochrome P450 (CYP) 3A4 is the major cause of drug-drug interactions (DDI). We have previously reported that the genetic variation of CYP3A4 significantly affected the inhibitory profiles of typical competitive inhibitors. In addition to competitive inhibition, some clinically significant DDI are attributable to mechanism-based inhibition (MBI). However, the differences in the M...

A series of fluoroquinolone compounds (compounds 1-9), which contain a common quinolone scaffold, inactivated the metabolic activity of CYP3A. The purpose of this study was to identify mechanism-based inhibition (MBI) among these fluoroquinolone compounds by metabolite profiling to elucidate the association of the substructure and MBI potential. Reversibility of MBI after incubation with potass...