The US psychologist Gail Hornstein's monograph, Agnes's Jacket: A Psychologist's Search for the Meanings of Madness (2009), is an important intervention in the identity politics of the mad movement. Hornstein offers a resignified vision of mad identity that embroiders the central trope of an "anti-colonial" struggle to reclaim the experiential world "colonized" by psychiatry. A series of litera...

BACKGROUND In 1992, the ICD-10 introduced the concept of mixed anxiety-depression disorder (MAD). However, a study examining the stability of this ICD-10-diagnosis is lacking. Our objective was to examine the 12 month outcome of MAD in comparison to the outcome of depression, anxiety, and comorbid depression and anxiety. METHODS 85 MAD patients, 496 patients with major depression, 296 patient...

In the vertebrates, the BMP/Smad1 and TGF-beta/Smad2 signaling pathways execute antagonistic functions in different contexts of development. The differentiation of specific structures results from the balance between these two pathways. For example, the gastrula organizer/node of the vertebrates requires a region of low Smad1 and high Smad2 signaling. In Drosophila, Mad regulates tissue determi...

This paper presents a revised rate control scheme based on an improved frame complexity measure. Rate control adopted by both MPEG-4 VM18 and H.264/AVC use a quadratic rate-distortion (R-D) model that determines quantization parameters (QPs). Classical quadratic R-D model is suitable for MPEG-4 but it performs poorly for H.264/AVC because one of the important parameters, mean absolute differenc...

In this paper, we consider the problem of incorporating a wide set of real-world trading constraints to the meanvariance portfolio framework. Instead of using the mean-variance model directly, we use the equivalent Mean-Absolute Deviation (MAD) linear programming formulation. The addition of the trading constraints transforms the MAD model to a mixed-integer linear programming problem. We solve...

Rational numbers are used to classify maximal almost disjoint (MAD) families of subsets of the integers. Combinatorial characterization of indestructibility of MAD families by the likes of Cohen, Miller and Sacks forcings are presented. Using these it is shown that Sacks indestructible MAD family exists in ZFC and that b = c implies that there is a Cohen indestructible MAD family. It follows th...