Let Holnx0(CP 1,X) be the space of based holomorphic maps of degree n from CP1 into a simply connected algebraic variety X. Under some condition we prove that the map Holnx0(CP 1,X) −→ Hol x0 (CP 1,X) obtained by compositing f ∈ Holnx0(CP 1,X) with g(z) = z, z ∈ CP1 induces rational homotopy equivalence up to some dimension, which tends to infinity as the degree grows.

Here we solve N × N Riemann-Hilbert (inverse monodromy) problems with all monodromy matrices having the structure of matrices of quasi-permutation (i.e. matrices which have only one non-zero element in each column and each row). Such RiemannHilbert problem may be associated to arbitrary Hurwitz space of algebraic curves L of genus g realized as N -sheeted covering over CP1, and allowes solution...

Mitochondrial processing peptidase (MPP) consists of α and β subunits that catalyze the cleavage of N-terminal mitochondrial-targeting sequences (N-MTSs) and deliver preproteins to the mitochondria. In plants, both MPP subunits are associated with the respiratory complex bc1, which has been proposed to represent an ancestral form. Subsequent duplication of MPP subunits resulted in separate sets...

Acupuncture can be regarded as a complex somatosensory stimulation. Here, we evaluate whether the point locations chosen for a somatosensory stimulation with acupuncture needles differently change the brain activity in healthy volunteers. We used EEG, event-related fMRI, and resting-state functional connectivity fMRI to assess neural responses to standardized needle stimulation of the acupunctu...

BACKGROUND We have shown that a low glutathione concentration and synthesis rate in erythrocytes are associated with a shortage of protein-derived cysteine in children with edematous severe acute malnutrition (SAM). OBJECTIVE We tested the hypothesis that methionine supplementation may increase protein-derived cysteine and upregulate cysteine synthesis, thereby improving glutathione synthesis...

Eighty consecutive patients were transplanted with human leukocyte antigen (HLA)-identical sibling marrow for acute myelogenous leukemia (AML, N = 29), acute lymphoid leukemia (ALL, N = 23), or chronic myelogenous leukemia (CML, N = 28). Donor marrow was depleted of lymphocytes using counterflow centrifugation. Median age of the recipients was 31 years. Pretransplant conditioning consisted of c...

Paleotemperatures based on ?18O values derived from belemnites are usually “too cold” compared to other archives and paleoclimate models. This temperature bias represents a significant obstacle in paleoceanographic research. Here we show geochemical evidence that belemnite calcite fibers composed of two distinct low-Mg phases (CP1, CP2). Phase-specific situ measurement revealed systematic offse...