Our previous studies clearly demonstrated that a combination of WP 631 and Epo B has higher activity against ovarian cancer cells than either of these compounds used separately. In order to fully understand the exact mechanism of action in combination, we assessed effects on the cell cycle of SKOV-3 cells. We evaluated three control points essential for WP 631 and Epo B action to determine whic...

There has been little information regarding the impact of unrecognised brain infarctions (UBIs) on stroke outcome in patients with non-valvular atrial fibrillation (NVAF). By using volumetric analysis of ischaemic lesions, we evaluated the potential impact of UBIs on clinical outcome according to their presence and categorised type. This study enrolled 631 patients with NVAF having no clinical ...

Dr. Waldman is Professor of Dental Health Services, School of Dental Medicine, SUNY at Stony Brook; Dr. Perlman is Global Clinical Director, Special Olympics, Special Smiles and Associate Clinical Professor of Pediatric Dentistry, Goldman School of Dental Medicine, Boston University. Direct correspondence to Dr. H. Barry Waldman, Professor of Dental Health Services, Department of General Dentis...

Cite this article: Du C, Volkow ND, Pan Y (2013) In vivo Optical Neuroimaging: Technological Development to Fit the Needs for Studying Drug-Induced Brain Functional Changes. JSM Biotechnol Bioeng 1(2): 1013. Corresponding author Congwu Du, Department of Biomedical Engineering, State University of New York at Stony Brook, Life Science Bldg, Rm. 002, Stony Brook, NY 11794-5281, USA, Tel: 631 632-...

Phone: (+ 48 42) 631 32 16; Fax: (+48 42) 631 32 18; E-mail: [email protected] Fraunhofer Institute for Applied Polymer Research, D-14476 Golm, Germany University of Potsdam, Institute of Physics, D-14469 Potsdam, Germany SONY International GmbH, Materials Science Laboratories, D-70327 Stuttgart, Germany University of Wuppertal, Institute of Chemistry, D-42097 Wuppertal, Germany 6 Max-Pla...

Phosphorylation of Ser-627 is both necessary and sufficient for full activity of the expressed 35-kDa catalytic domain of myosin I heavy chain kinase (MIHCK). Ser-627 lies in the variable loop between highly conserved residues DFG and APE at a position at which a phosphorylated Ser/Thr also occurs in many other Ser/Thr protein kinases. The variable loop of MIHCK contains two other hydroxyamino ...

The imaging atmospheric Cherenkov array H.E.S.S. recently discovered an extended source in the 0.4−10 TeV energy range, HESS J1303−631. We obtained a 5 ks observation with the ACIS-I array on the Chandra X-ray observatory that does not reveal an obvious compact or diffuse X-ray counterpart. Archival ROSAT images are also blank in this region. Although there are several radio pulsars within the ...

J Am Med Inform Assoc. 2009;16:631–636. DOI 10.1197/jamia.M3033.