A marine arenicin-3 derivative, N4, displayed potent antibacterial activity against Gram-negative bacteria, but its antibacterial mode of action remains elusive. The mechanism of action of N4 against pathogenic Escherichia coli was first researched by combined cytological and transcriptomic techniques in this study. The N4 peptide permeabilized the outer membrane within 1 min, disrupted the pla...

In this paper we re-examine the alkali dependence of the fraction of four-coordinated borons (N4) in two series of glasses: alkali borates (0·4M2O.B2O3) and mixed lithium caesium borates (0·4(xLi2O+(1-x)Cs2O). B2O3). High field B MAS-NMR experiments were performed to maximise the accuracy of the present results. We found no evidence for an alkali dependence on N4 in either system. In each case ...

Two bacteriophages, DSS3Phi2 and EE36Phi1, which infect marine roseobacters Silicibacter pomeroyi DSS-3 and Sulfitobacter sp. EE-36, respectively, were isolated from Baltimore Inner Harbor water. These two roseophages resemble bacteriophage N4, a large, short-tailed phage infecting Escherichia coli K12, in terms of their morphology and genomic structure. The full genome sequences of DSS3Phi2 an...

The author uses irrationality and linear independence measures for certain algebraic numbers to derive explicit upper bounds for the solutions of related norm form equations. The Lenstra-Lenstra-Lovász lattice basis reduction algorithm is then utilized to show that the integer solutions to NK/Q(x 4 √ N4 − 1 + y 4 √ N4 + 1 + z) = ±1 (where K = Q( 4 √ N4 − 1, 4 √ N4 + 1)) are given by (x, y, z) =...

We estimate analytically the critical coupling separating the weak and the strong coupling regime in 4D simplicial quantum gravity to be located at kcrit 2 ≃ 1.3093. By carrying out a detailed geometrical analysis of the strong coupling phase we argue that the distribution of dynamical triangulations with singular vertices, dominating in such a regime, is characterized by distinct sub-dominatin...