Our previous study demonstrated a decreased expression of tumor susceptibility gene 101 (TSG101) in cervical cancer cells. To identify the mechanism responsible for TSG101 downregulation during cervical cancer development, we analyzed the TSG101 promoter using cis-element cluster finder software. One of the transcription factors whose binding site was detected in the TSG101 promoter was late SV...

To achieve high coding efficiency, modern speech coders adopt hybrid coding approaches, which utilize different coding mechanisms for various classified speech segments. With known voiced/unvoiced detection, in this paper, a classified LPC quantization (CLPQ) scheme is presented to effectively encode line spectral frequencies (LSF). The proposed CLPQ scheme improves the performance of the class...

Research exploring the role of spatial frequencies in rapid stimulus detection and categorization report flexible reliance on specific spatial frequency (SF) bands. Here, through a set of behavioral and magnetoencephalography (MEG) experiments, we investigated the role of low spatial frequency (LSF) (<8 cycles/face) and high spatial frequency (HSF) (>25 cycles/face) information during the categ...

Line spectral frequencies (LSF) are widely used in the field of speech coding. Due to its properties, the LSF are qualified for the quantisation and the efficient compression of speech signals. In this paper we introduce the line cepstral quefrencies (LCQ). They are derived from the cepstrum in the same manner as the LSF are derived from linear predictive coding (LPC) features. We show that the...

In this paper, we investigate a novel method for transforming line spectral frequency (LSF) parameters to lower dimensional coefficients. Radial basis function neutral network (RBF NN) based transforming model is used to fit LSF vectors. In the training process, two criterions, including mean squared error and weighted mean squared error, are involved to measure distance between original vector...

The local scattering function (LSF) and the generalized channel correlation function have recently been introduced as intuitive and useful statistical characterization of fading channels that do not satisfy the usual WSSUS assumption [1]. In this paper, we present a generalized LSF and we demonstrate that for the subclass of practically relevant doubly underspread non-WSSUS channels, several us...

The therapeutic application of high-dose interleukin (IL) 2 in human malignancy is limited by severe multiorgan toxicities that are mediated, in part, by tumor necrosis factor (TNF) and IL-1. CT1501R (lisofylline; LSF) is one of several methyl xanthine congeners that inhibit the effects of TNF by the interruption of specific signal transduction pathways. This randomized, placebo-controlled tria...

Line spectral frequencies (LSF) and immittance spectral frequencies (ISF) are widely used in modern speech codecs based on autoregressive model. This paper addresses LSF and ISF calculation problems. The investigation of LSF/ISF placement on adjacent quasi-stationary frames is performed. It is shown that in majority of cases the inter-frame ordering property takes place. On this basis a new app...