Interprotein contact prediction using multiple sequence alignments (MSAs) is a useful approach to help detect protein-protein interfaces. Different computational methods have been developed in recent years as an approximation to solve this problem. However, as there are discrepancies in the results provided by them, there is still no consensus on which is the best performing methodology. To add...

The d-dimensional Euclidean space Rd is the d-dimensional vector space over the real numbers R where we have the familiar notions of distances and angles from classical plane geometry. The space Rd is comprised of vectors (or points), which can be added (z := x + y for x,y ∈ Rd) and scaled by real numbers (z := cx for c ∈ R and x ∈ Rd) to obtain other vectors in Rd. Every vector x ∈ Rd has a (E...

f(x) = { 1 if wx+ b > 0, −1 otherwise. Consider d+1 points x = (0, ..., 0) , x = (1, 0, ..., 0) , x = (0, 1, ..., 0) , ..., x = (0, 0, ..., 1) . After these d+1 points being arbitrarily labeled: y = (y0, y1, ..., yd) T ∈ {−1, 1}. Let b = 0.5 · y0 and w = (w1, w2, ...wd) where wi = yi, i ∈ {1, 2, ..., d}. Thus f(x) can label all these d+ 1 points correctly. So the VC dimension of perceptron is a...

PURPOSE A recent reanalysis of the Collaborative Ocular Melanoma Study (COMS) medium tumor trial concluded that incorporating factors to account for anisotropy, line source approximation, the gold plaque, and attenuation in the Silastic seed carrier into the dose calculations resulted in a significant and consistent reduction of calculated doses to structures of interest within the eye. The aut...

Purpose Determine which posterior uveal melanoma (PUM) size classification with three categories has the best prognostic discrimination. Methods Single-institution study of 424 consecutive patients with PUM. The tumor's largest basal diameter (LBD), smallest basal diameter (SBD), and thickness (TH) were estimated by fundus mapping and ultrasonography. Tumors were assigned to "small," "medium,...

Competence is a physiological state that enables Bacillus subtilis 168 to take up and internalize extracellular DNA. In practice, only a small subpopulation of B. subtilis 168 cells becomes competent when they enter stationary phase. In this study, we developed a new transformation method to improve the transformation efficiency of B. subtilis 168, specially in rich media. At first, different c...

Communication, Ocean and Meteorological Satellite (COMS) is the first Korean geostationary satellite, which is located in 128.2°E launched in 2010, and it is currently under normal operation. Atmospheric motion vectors (AMVs) derived with high resolution satellite images are useful for analyzing mesoscale motion such as convective clouds and ageostrophic flow. National Institute of Meteorologic...