Partial loss and subsequent recovery of cochlear implant function in the first few weeks following cochlear implant surgery has been observed in previous studies using psychophysical detection thresholds. In the current study, we explored this putative manifestation of insertion trauma using objective functional measures: electrically-evoked compound action potential (ECAP) amplitude-growth fun...

The effect of surface electrode positioning on the evoked compound action potential (ECAP) was studied during inhalation anaesthesia without neuromuscular blockade. The ECAP of five full-term infants (aged 2-20 weeks) and five children (age 1-10 yr) was recorded with a neuromuscular relaxation monitor (Relaxograph, Datex) after supramaximal ulnar nerve stimulation. The five recording electrode ...

A spray-cast Al-7034 alloy was processed by equal-channel angular pressing (ECAP) to a total of 8 passes at 473 K and the pressed samples were examined using transmission electron microscopy, differential scanning calorimetry and electron back-scatter diffraction. It is shown that the grain size of the alloy is reduced to ~0.3 μm by ECAP and the high pressures associated with ECAP lead to a fra...

Closed-loop deep brain stimulation (DBS) systems could provide automatic adjustment of stimulation parameters and improve outcomes in the treatment of Parkinson's disease and essential tremor. The evoked compound action potential (ECAP), generated by activated neurons near the DBS electrode, may provide a suitable feedback control signal for closed-loop DBS. The objectives of this work were to ...

49 Closed-loop deep brain stimulation (DBS) systems could provide automatic adjustment of stimulation 50 parameters and improve outcomes in the treatment of Parkinson's disease and essential tremor. The 51 evoked compound action potential (ECAP), generated by activated neurons near the DBS electrode, may 52 provide a suitable feedback control signal for closed-loop DBS. The objectives of this w...

In this study we aim to resolve the contributions of facilitation and refractoriness at very short pulse intervals. Measurements of the refractory properties of the electrically evoked compound action potential (ECAP) of the auditory nerve in cochlear implant (CI) users at inter pulse intervals below 300 μs are influenced by facilitation and recovery effects. ECAPs were recorded using masker pu...

This study investigated the effects of acoustic noise on the auditory nerve compound action potentials in response to electric pulse trains. Subjects were adult guinea pigs, implanted with a minimally invasive electrode to preserve acoustic sensitivity. Electrically evoked compound action potentials (ECAP) were recorded from the auditory nerve trunk in response to electric pulse trains both dur...

Microstructure evolutions and mechanical properties of a commercially pure titanium (CP-Ti, grade 2) during multi-pass rotary-die equal-channel angular pressing (RD-ECAP) and cold rolling (CR) were systematically investigated in this work, to achieve comprehensive property for faster industrial applications. The obtained results showed that the grain size of CP-Ti decreased from 80 μm of as-rec...

In children with cochlear implant (CI), the recording of the electrically evoked compound action potential (ECAP) of the auditory nerve represents an option to assess changes in auditory nerve responses and the interaction between the electrode bundle and the neural tissue over time. Aim: To study ECAP in children during the first year of CI use. Materials and methods: The ECAP characteristics ...