نتایج جستجو برای: طیف lpc

تعداد نتایج: 22729  

2005
G. Dolezel M. P. Cucuianu E. E. Nishizawa

The effects of lysolecithin (LPC) on aggregation, serotonin release, shape, and lysis of rabbit, pig, or human platelets in platelet-rich plasma (PRP) or Tyrode albumin solution were examined during prolonged incubation. LPC added to citrated or heparinized PRP from humans or rabbits at a final concentration above 100 uM caused instantaneous inhibition of platelet aggregation induced by adenosi...

2015
Yu-ju Kanayama Masakazu Kaneko Yoshiko Emoto Masashi Emoto

Human E-cadherin and listeriolysin O (LLO) are involved in invasion of Listeria monocytogenes into human liver parenchymal cells (LPC). Yet, it remains to be determined whether murine E-cadherin and LLO participate in invasion of L. monocytogenes into murine LPC. In the present study, involvement of murine E-cadherin and LLO in invasion of L. monocytogenes into murine LPC was investigated. Muri...

Journal: :Clinical chemistry 2002
Gerhard Liebisch Wolfgang Drobnik Bernd Lieser Gerd Schmitz

BACKGROUND Lysophosphatidylcholine (LPC) has been suggested to play a functional role in various diseases, including atherosclerosis, diabetes, and cancer mediated by LPC-specific G-protein-coupled receptors. Initial studies provided evidence for a potential use of LPC as diagnostic maker. However, existing methodologies are of limited value for a systematic evaluation of LPC species concentrat...

Journal: :Bioscience, biotechnology, and biochemistry 2002
Koji Ishizuka Yusei Miyamoto Hideo Satsu Ryuichiro Sato Makoto Shimizu

The characteristics of lysophosphatidylcholine (LPC) in its inhibition of the taurine uptake by human intestinal Caco-2 cells were investigated. By treating the cells with 200 microM of LPC, the taurine uptake was rapidly decreased by approximately 60%. This decrease was accompanied by an increase in the Km value for the uptake. A rapid uptake of LPC itself by the cells was also observed. The i...

Journal: :Journal of pharmacological sciences 2003
Hiroshi Suenaga Katsuo Kamata

We previously reported that in the endothelium-denuded rat aorta, lysophosphatidylcholine (LPC) potentiates the contractile responses induced by high-K(+), UK14,304 (a selective alpha(2)-adrenoceptor agonist), and phorbol ester with an associated tyrosine-phosphorylation of proteins. To further investigate this phenomenon, we examined the effects of extracellular-signal-regulated protein kinase...

2014
Hyung-Suk Kim

Linear predictive coding (LPC) is a widely used technique in audio signal processing, especially in speech signal processing. It has found particular use in voice signal compression, allowing for very high compression rates. As widely adopted as it is, LPC is covered in many textbooks and is taught in most advanced audio signal processing courses. So why another article on LPC? Despite covering...

Journal: :American journal of physiology. Heart and circulatory physiology 2003
Hazel Lum Jing Qiao Robert J Walter Fei Huang Papasani V Subbaiah Kwang S Kim Oksana Holian

The atherogenic serum lysophosphatidylcholine (LPC) is known to mediate vascular endothelial responses ranging from upregulation of adhesion molecules and growth factors to secretion of chemokines and superoxide anion. We investigated whether endothelial cells express receptors for LPC, which may account for their actions. Human brain microvascular (HBMEC) and dermal microvascular endothelial c...

Journal: :Journal of molecular and cellular cardiology 2004
Christoph Rüdiger Wolfram Kuhlmann Dörte Wiebke Lüdders Christian Alexander Schaefer Astrid Kerstin Most Ulrich Backenköhler Thomas Neumann Harald Tillmanns Ali Erdogan

Proliferation of endothelial cells plays a crucial role in the process of atherosclerotic plaque destabilization. The major component of oxidized low-density lipoprotein lysophosphatidylcholine (LPC) has been shown to promote endothelial proliferation by increasing the production of reactive oxygen species (ROS). Since K(+) channels are known to control the cell cycle, we investigated the role ...

Journal: :Blood 1977
J H Joist G Dolezel M P Cucuianu E E Nishizawa J F Mustard

The effects of lysolecithin (LPC) on aggregation, serotonin release, shape, and lysis of rabbit, pig, or human platelets in platelet-rich plasma (PRP) or Tyrode albumin solution were examined during prolonged incubation. LPC added to citrated or heparinized PRP from humans or rabbits at a final concentration above 100 muM caused instantaneous inhibition of platelet aggregation induced by adenos...

Journal: :American journal of physiology. Lung cellular and molecular physiology 2005
Fei Huang Papasani V Subbaiah Oksana Holian Jihang Zhang Arnold Johnson Nancy Gertzberg Hazel Lum

Lysophosphatidylcholine (LPC) is a bioactive proinflammatory lipid that can be generated by pathological activities. We investigated the hypothesis that LPC signals increase in endothelial permeability. Stimulation of human dermal microvascular endothelial cells and bovine pulmonary microvascular endothelial cells with LPC (10-50 microM) induced decreases (within minutes) in transendothelial el...

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