1 Department of Epidemiology & Bio-statistics, Chittaranjan National Cancer Institute, Calcutta, India. 2 Health Services Research, St. Louis University School of Public Health, St. Louis, MO 63108 Address for Correspondence: Dr. Urmi Sen, Department of Epidemiology and Biostatistics, Chittaranjan National Cancer Institute 37, S.P. Mukherjee Road, Calcutta 700026, Fax: 91-33-475 7606, e-mail: u...

Computational steering is a technique that combines simulation and visualization. The user is continuously provided with visual feedback about the state of the simulation, and can change parameters on the y. Designers can vary parameters to optimize their product, users can detect errors in the input early, researchers can do qualitative sensitivity analyses easily. The implementation of comput...

We present a method for the deenition of multiple views in 3D interfaces for computational steering. The method uses the concept of a point-based parametrizable camera object. This concept enables a user to create and conngure multiple views on his custom 3D interface in an intuitive graphical manner. Each view can be coupled to objects present in the interface, parametrized to (simulation) dat...

1 Department of Oral and Maxillofacial Surgery, The Sixth Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, P.R.China. 2 Department of Periodontology, Sun Yat-Sen Memorial Hospital of Sun Yat-sen University, Guangzhou, Guangdong, P.R. China. 3 Department of Oncological Radiotherapy, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, Guangdong, P.R. China. Intern...

1 Department of Oral and Maxillofacial Surgery, The Sixth Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, P.R.China. 2 Department of Periodontology, Sun Yat-Sen Memorial Hospital of Sun Yat-sen University, Guangzhou, Guangdong, P.R. China. 3 Department of Oncological Radiotherapy, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, Guangdong, P.R. China. Intern...

Zhen-wei Liang,* Zheng Wang,* Hui Chen, Cen Li, Ti Zhou, Zhonghan Yang, Xia Yang, Yanfang Yang, Guoquan Gao,* and Weibin Cai* Department of Biochemistry, Zhongshan Medical School, Sun Yat-sen University, Guangzhou, Guangdong Province, China; Department of Obstetrics and Gynecology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province, China; Key Laboratory of F...

Streptococcal surface enolase (SEN) is a major plasminogen-binding protein of group A streptococci. Our earlier biochemical studies have suggested that the region responsible for this property is likely located at the C-terminal end of the SEN molecule. In the present study, the gene encoding SEN was cloned from group A streptococci M6 isolate D471. A series of mutations in the sen gene corresp...

Senecionine (SEN) is a representative of the hepatotoxic pyrrolizidine alkaloids. Although phase I metabolism for cytochrome P450-mediated metabolic activation of SEN was investigated extensively, phase II metabolism for glucuronidation of this compound has not been investigated until now. In our present study, one unique glucuronidation product of SEN in human liver microsomes (HLMs) was ident...