A small model polypeptide represented in atomic detail is folded using Monte Carlo dynamics. The polypeptide is designed to have a native conformation similar to the central part of the helix-turn-helix protein ROP. Starting from a β-strand conformation or two different loop conformations of the protein glutamine synthetase, six trajectories are generated using the so-called window move in dihe...

2010;56;1267-1282; originally published online Sep 21, 2010; J. Am. Coll. Cardiol. Park, and Jeffrey J. Popma Seung-Jung Day, Roger Hall, Martin B. Leon, Ziyad M. Hijazi, Francis Marchlinski, Gregory J. Dehmer, John S. Douglas, Jr, Alexander Abizaid, Jessica W. Berg, John Standards for the Future Demonstrations at Cardiology Meetings: Assessments of the Past and SCAI/ACCF/HRS/ESC/SOLACI/APSIC S...

The diagnosis of familial defective apolipoprotein B-100 (FDB) has been facilitated by the use of mutagenic polymerase chain reaction (PCR) primers to introduce restriction sites at the FDB gene locus. We describe a two-test strategy for diagnosing FDB that overcomes the potential for error in single-test methods based on such techniques. We introduce an Sau96I restriction site for PCR products...

The SCAI instrument was designed to help clinicians estimate the economic aspects of the provision of assistive technology (AT) solutions to individual users. Using the instrument involves three steps: 1) describing the objectives of the individual AT programme 2) establishing the sequence and the timing of all the interventions that form the programme and 3) compiling a cost calculation table ...

he Clinical Development of ercutaneous Heart Valve Technology Position Statement of the Society of Thoracic Surgeons (STS), he American Association for Thoracic Surgery (AATS), and he Society for Cardiovascular Angiography and Interventions (SCAI) ndorsed by the American College of Cardiology Foundation (ACCF) nd the Society for Cardiovascular Angiography and Interventions ublished by Elsevier ...

Atrial natriuretic peptide (ANP) jointly affects kidney function and blood pressure homeostasis and is a candidate susceptibility gene for both essential hypertension and kidney disease. We evaluated the relation between the ScaI and BstXI polymorphisms of the human ANP (hANP) gene, hypertension, and albuminuria in a clinical cohort of 1033 subjects, including type 1 and type 2 diabetic patient...